Caspase 9 抗体 (AA 141-392)
Quick Overview for Caspase 9 抗体 (AA 141-392) (ABIN7112370)
抗原
See all Caspase 9 (CASP9) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 141-392
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原理
- CASP9 antibody
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纯化方法
- Protein A+G purification
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
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Immunogen sequence: 141-392aa
Immunogen: caspase 9, apoptosis-related cysteine peptidase
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亚型
- IgG1
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应用备注
- WB: 1:500-1:2000, IP: 1:500-1:1000, IHC: 1:100-1:400, IF: 1:50-1:500
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- Caspase 9 (CASP9) (Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9))
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别名
- CASP9
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背景
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Synonyms: Caspase-9 (CASP-9)|Apoptotic protease Mch-6|Apoptotic protease-activating factor 3 (APAF-3)|ICE-like apoptotic protease 6 (ICE-LAP6)|Caspase-9 subunit p35|Caspase-9 subunit p10|CASP9|MCH6
Background: Caspase 9, apoptosis-related cysteine protease(CASP9, synonyms: MCH6, APAF3, APAF-3, ICE-LAP6, CASPASE-9c)is a member of the cysteine-aspartic acid protease(caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. Caspase 9 is processed by APAF1, this step is thought to be one of the earliest in the caspase activation cascade
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分子量
- 46 kDa, 36 kDa
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基因ID
- 842
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UniProt
- P55211
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途径
- MAPK Pathway, RTK signaling, Apoptosis, Caspase Cascade in Apoptosis, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Endopeptidase Activity
抗原
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