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Caspase 8 抗体 (AA 1-270)

Name: Caspase 8 抗体 (AA 1-270)
Brand: antibodies-online
SKU: ABIN7112367
Availability: OutOfStock

This anti-Caspase 8 antibody is a 小鼠单克隆 antibody detecting Caspase 8 in WB, IHC, ELISA, IP 和 IF. Suitable for 人.

产品编号 ABIN7112367

发货至: 中国

Quick Overview for Caspase 8 抗体 (AA 1-270) (ABIN7112367)

抗原

See all Caspase 8 (CASP8) 抗体

Caspase 8 (CASP8)

适用

人

宿主

小鼠

克隆类型

单克隆

标记

This Caspase 8 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF)

克隆位点

2C2

Discover our top product CASP8 Primary Antibody

抗原表位
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AA 1-270

原理

CASP8 antibody

纯化方法

Protein A+G purification

纯度

≥95 % as determined by SDS-PAGE

免疫原

Immunogen sequence: 1-270aa
Immunogen: caspase 8, apoptosis-related cysteine peptidase

亚型

IgG1
anti-Caspase 8 (CASP8) (AA 411-482) antibody
CASP8 适用: 人, 小鼠, 大鼠, 猴, Pig, 绵羊 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Caspase 8 (CASP8) (AA 1-479) antibody
CASP8 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Caspase 8 (CASP8) (AA 188-280) antibody
CASP8 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Caspase 8 (CASP8) (AA 217-384) antibody
CASP8 适用: 人 WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated

anti-Caspase 8 (CASP8) (AA 7-201) antibody
CASP8 适用: 人 WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated

anti-Caspase 8 (CASP8) (AA 385-479) antibody
CASP8 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated

anti-Caspase 8 (CASP8) antibody
CASP8 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 1H11 unconjugated

anti-Caspase 8 (CASP8) (AA 410-449), (N-Term) antibody
CASP8 适用: 人, 小鼠, 大鼠 WB, IHC, ICC, FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Caspase 8 (CASP8) (AA 217-374) antibody
CASP8 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Caspase 8 (CASP8) antibody
CASP8 适用: 小鼠 WB, IHC, ELISA, ICC, FACS 宿主: 大鼠 Monoclonal 3B10 unconjugated

应用备注

WB: 1:500-1:5000, IP: 1:200-1:2000, IHC: 1:100-1:400, IF: 1:50-1:500

限制

仅限研究用
状态

Liquid

缓冲液

PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze / thaw cycles.

储存条件

-20 °C

储存方法

-20°C for 12 months

有效期

12 months
抗原

Caspase 8 (CASP8)

别名

CASP8

背景

Synonyms: Caspase-8 (CASP-8)|Apoptotic cysteine protease|Apoptotic protease Mch-5|CAP4|FADD-homologous ICE/ced-3-like protease|FADD-like ICE (FLICE)|ICE-like apoptotic protease 5|MORT1-associated ced-3 homolog (MACH)|Caspase-8 subunit p18|Caspase-8 subunit p10|CASP8|MCH5
Background: Caspase 8, also named as MCH5, MACH, FLICE, and CAP4, belongs to the peptidase C14A family. It may participate in the GZMB apoptotic pathways and functions as an upstream regulator in a-bisabolol-induced apoptosis. Caspase 8 catalyzes an essential intermediate step in the ubiquitination and proteasome-mediated degradation of IRF3(PMID:21816816). It may control diabetic embryopathy-associated apoptosis via Caspase 8 is expressed as nine isoforms by alternative splicing with the molecular mass from 26 kDa to 62 kDa. This antibody can recognize pro-and cleaved-caspase 8.

分子量

50-55 kDa, 25-32 kDa

基因ID

841

UniProt

Q14790

途径

Apoptosis, Caspase Cascade in Apoptosis, TLR signaling, Activation of Innate immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades