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BBS7 抗体

BBS7 适用: 人, 小鼠, 大鼠 ELISA, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7111937
发货至: 中国
  • 抗原 See all BBS7 抗体
    BBS7 (Bardet-Biedl Syndrome 7 (BBS7))
    适用
    人, 小鼠, 大鼠
    宿主
    • 27
    • 3
    • 1
    克隆类型
    • 29
    • 2
    多克隆
    标记
    • 17
    • 4
    • 3
    • 3
    • 2
    • 2
    This BBS7 antibody is un-conjugated
    应用范围
    • 26
    • 20
    • 3
    • 3
    • 1
    • 1
    ELISA, Immunofluorescence (IF)
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    Bardet-Biedl syndrome 7
    亚型
    IgG
    Top Product
    Discover our top product BBS7 Primary Antibody
  • 应用备注
    IF: 1:20-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    BBS7 (Bardet-Biedl Syndrome 7 (BBS7))
    别名
    BBS7 (BBS7 产品)
    别名
    BBS7 antibody, bbs2l1 antibody, BBS2L1 antibody, id:ibd5048 antibody, zgc:153772 antibody, 8430406N16Rik antibody, Bardet-Biedl syndrome 7 antibody, bardet-biedl syndrome 7 antibody, Bardet-Biedl syndrome 7 L homeolog antibody, Bardet-Biedl syndrome 7 (human) antibody, BBS7 antibody, bbs7 antibody, MICPUN_100192 antibody, MICPUCDRAFT_16331 antibody, bbs7.L antibody, Bbs7 antibody
    背景
    Synonyms:BBS2L1 Background:The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor(GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. The BBSome complex, together with the LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog(SHH) pathway regulation. Required for proper BBSome complex assembly and its ciliary localization.
    分子量
    80 kDa
    基因ID
    55212
    UniProt
    Q8IWZ6
    途径
    Hedgehog Signaling
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