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MHC Class II HLA-DP/DQ/DR 抗体 (Biotin)

This anti-MHC Class II HLA-DP/DQ/DR antibody is a 小鼠 单克隆 antibody detecting MHC Class II HLA-DP/DQ/DR in FACS. Suitable for 人.
产品编号 ABIN7077536
发货至: 中国

Quick Overview for MHC Class II HLA-DP/DQ/DR 抗体 (Biotin) (ABIN7077536)

抗原

MHC Class II HLA-DP/DQ/DR (HLA-DP/DQ/DR)

适用

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  • 1

宿主

  • 25
  • 12
小鼠

克隆类型

  • 37
单克隆

标记

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This MHC Class II HLA-DP/DQ/DR antibody is conjugated to Biotin

应用范围

  • 35
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Flow Cytometry (FACS)

质量等级

GMP Grade

克隆位点

IVA12
  • 原理

    Anti-HLA-DR, DP, DQ Biotin Antibody

    产品特性

    The clone IVA12 recognizes the shared epitopes of human leukocyte antigen (HLA) class II molecules HLA-DP, HLA-DQ and HLA-DR heterodimeric cell surface glycoproteins comprised of an α (heavy) chain and a β (light) chain. They are expressed on B cells, activated T cells, monocytes/macrophages, dendritic cells, and other non-professional antigen presenting cells (APCs). HLA-Class II expressing APCs specifically present antigens recognized by TCR/CD3 complex of CD4+ T cells. Reactive microglia and perivascular cells in multiple sclerosis lesions express all three types of HLA-Class II molecules, whereas microglia in the normal CNS express HLA-DR only.

    纯化方法

    Purified

    纯度

    >95 %

    免疫原

    Priess human B cell line

    亚型

    IgG1, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS pH 7.2, 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    2-8°C, Conjugated antibodies should never be frozen.
  • 抗原

    MHC Class II HLA-DP/DQ/DR (HLA-DP/DQ/DR)

    别名

    HLA-DR, DP, DQ

    途径

    Human Leukocyte Antigen (HLA) in Adaptive Immune Response
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