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ULBP2 抗体

ULBP2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7076145
发货至: 中国
  • 抗原 See all ULBP2 抗体
    ULBP2 (UL16 Binding Protein 2 (ULBP2))
    适用
    • 23
    • 1
    • 1
    宿主
    • 18
    • 5
    克隆类型
    • 20
    • 3
    多克隆
    标记
    • 13
    • 2
    • 2
    • 2
    • 2
    • 2
    This ULBP2 antibody is un-conjugated
    应用范围
    • 21
    • 15
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    Affinity purification
    免疫原
    Recombinant protein corresponding to Human ULBP2
    Top Product
    Discover our top product ULBP2 Primary Antibody
  • 应用备注
    WB (H) 1:500- 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS, pH 7.4, 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • 抗原
    ULBP2 (UL16 Binding Protein 2 (ULBP2))
    别名
    ULBP2 (ULBP2 产品)
    别名
    N2DL2 antibody, RAET1H antibody, UL16 binding protein 2 antibody, NKG2D ligand 2-like antibody, ULBP2 antibody, LOC100355436 antibody
    背景
    ULBP2 is a human ligand for the NKG2D receptor, together with at least ULBP1 and ULBP3. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway. The interaction with UL16 blocks the interaction with the NKG2D receptor, providing a mechanism by which CMV infected cells might escape the immune system UL16 also causes ULBP2 to be retained in the ER and cis-Golgi apparatus so that it does not reach the cell surface. ULBP2 is expressed in various types of cancer cell lines and in the fetus, but not in normal tissues.
    分子量
    37 kDa
    基因ID
    80328
    NCBI登录号
    NP_079493
    UniProt
    Q9BZM5
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