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TFG 抗体

TFG 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7076022
发货至: 中国
  • 抗原 See all TFG 抗体
    TFG (Trk-Fused Gene (TFG))
    适用
    • 50
    • 14
    • 9
    宿主
    • 44
    • 6
    克隆类型
    • 38
    • 12
    多克隆
    标记
    • 23
    • 5
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TFG antibody is un-conjugated
    应用范围
    • 42
    • 27
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    Affinity purification
    免疫原
    Recombinant protein corresponding to Human TRK fused gene
    Top Product
    Discover our top product TFG Primary Antibody
  • 应用备注
    WB (H) 1:500- 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS, pH 7.4, 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • 抗原
    TFG (Trk-Fused Gene (TFG))
    别名
    TRK fused gene (TFG 产品)
    别名
    wu:fb11c10 antibody, zgc:55342 antibody, zgc:77230 antibody, HMSNP antibody, SPG57 antibody, TF6 antibody, TRKT3 antibody, AI173908 antibody, trk-fused gene antibody, TRK-fused gene antibody, Trk-fused gene antibody, tfg antibody, TFG antibody, Tfg antibody
    背景
    Protein TFG (TRK-fused gene protein) plays a role in regulating phosphotyrosine-specific phosphatase-1 activity. Mutations in TFG may have important clinical relevance for current therapeutic strategies to treat metastatic melanoma. Defects in TFG are a cause of thyroid papillary carcinoma (TPC), a common tumor of the thyroid that typically arises as an irregular, solid or cystic mass from otherwise normal thyroid tissue. Recent genetic investigation indicates that formation of TFG-containing cytoplasmic inclusions and concomitant mislocalization of TAR DNA-binding protein 43 kDa (TDP-43) underlie motor neuron degeneration in HMSN-P. Pathological overlap of proteinopathies involving TFG and TDP-43 highlights a new pathway leading to motor neuron degeneration.
    分子量
    55 kDa
    基因ID
    10342
    UniProt
    Q92734
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