电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

PKD1 抗体

PKD1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7075124
发货至: 中国
  • 抗原 See all PKD1 抗体
    PKD1 (Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1))
    适用
    • 39
    • 27
    • 10
    • 1
    • 1
    宿主
    • 38
    • 1
    克隆类型
    • 39
    多克隆
    标记
    • 14
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PKD1 antibody is un-conjugated
    应用范围
    • 25
    • 17
    • 14
    • 13
    • 13
    • 7
    • 7
    • 3
    • 3
    • 1
    Western Blotting (WB)
    交叉反应
    纯化方法
    Affinity purification
    免疫原
    Recombinant protein corresponding to Mouse Polycystin 1
    Top Product
    Discover our top product PKD1 Primary Antibody
  • 应用备注
    WB (H) 1: 500-1: 1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS, pH 7.4, 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • 抗原
    PKD1 (Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1))
    别名
    Polycystin 1 (PKD1 产品)
    别名
    PBP antibody, Pc-1 antibody, TRPP1 antibody, PC1 antibody, mFLJ00285 antibody, polycystin 1, transient receptor potential channel interacting antibody, polycystin 1, transient receptor poteintial channel interacting antibody, polycystin-1 antibody, PKD1 antibody, Pkd1 antibody, LOC749291 antibody
    背景
    This gene encodes a member of the polycystin protein family. The encoded glycoprotein contains a large N-terminal extracellular region, multiple transmembrane domains and a cytoplasmic C-tail. It is an integral membrane protein that functions as a regulator of calcium permeable cation channels and intracellular calcium homoeostasis. It is also involved in cell-cell/matrix interactions and may modulate G-protein-coupled signal-transduction pathways. Involved in renal tubulo genesis. Involved in fluid-flow mechano sensation by the primary cilium in renal epithelium (By similarity). Acts as a regulator of cilium length, together with PKD2 (By similarity). and mutations in this gene cause autosomal dominant polycystic kidney disease type 1 (ADPKD1). ADPKD1 is characterized by the growth of fluid-filled cysts that replace normal renal tissue and result in end-stage renal failure. Splice variants encoding different isoforms have been noted for this gene.
    分子量
    >460 kDa
    基因ID
    18763
    NCBI登录号
    NP_038658
    UniProt
    O08852
    途径
    Myometrial Relaxation and Contraction, Maintenance of Protein Location
You are here: