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NOTCH4 抗体

NOTCH4 适用: 人 IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7074863
发货至: 中国
  • 抗原 See all NOTCH4 抗体
    NOTCH4 (Notch 4 (NOTCH4))
    适用
    • 41
    • 29
    • 20
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    宿主
    • 55
    • 3
    • 2
    克隆类型
    • 49
    • 11
    多克隆
    标记
    • 32
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NOTCH4 antibody is un-conjugated
    应用范围
    • 29
    • 17
    • 13
    • 13
    • 6
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF)
    交叉反应
    纯化方法
    Affinity purification
    免疫原
    KLH conjugated Synthetic peptide corresponding to Mouse NOTCH4
    Top Product
    Discover our top product NOTCH4 Primary Antibody
  • 应用备注
    IHC/IF (H) 1:600-1:1200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS, pH 7.4, 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • 抗原
    NOTCH4 (Notch 4 (NOTCH4))
    别名
    Notch4 (NOTCH4 产品)
    别名
    INT3 antibody, NOTCH3 antibody, Int-3 antibody, Int3 antibody, N4 antibody, Notch4 antibody, notch 4 antibody, neurogenic locus notch homolog protein 4 antibody, NOTCH4 antibody, Notch4 antibody, LOC100712850 antibody
    背景
    Notch4 is a member of the Notch family. The Notch4 signaling network is an evolutionarily conserved intracellular pathway that regulates physical cell to cell interactions. The Notch4 protein, once cleaved from the trans-Golgi network, is presented on the cell surface as a heterodimer. Notch4 regulates cell-fate determination as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1. In Drosophila, once these ligands are activated via the release of the notch intracellular domain (NICD), Notch4 forms a transcriptional activator complex with RBPJ/RBPSUH which then activates the genes of the Enhancer of Split (E(spl)) locus. Notch4 also plays a role in vascular, renal and hepatic development, the implementation of differentiation, proliferation and apoptotic programs, and the regulation of branching morphogenesis in the development of the vascular system.
    基因ID
    18132
    NCBI登录号
    NP_035059
    UniProt
    P31695
    途径
    Notch Signaling
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