Presenilin 2 抗体 (AA 51-150) (HRP)
Quick Overview for Presenilin 2 抗体 (AA 51-150) (HRP) (ABIN704525)
抗原
See all Presenilin 2 (PSEN2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 51-150
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human presenilin 2/PS-2
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亚型
- IgG
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anti-Presenilin 2 (Alzheimer Disease 4) (PSEN2) (N-Term) antibody
PSEN2 适用: 人, 大鼠, 小鼠 WB, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Presenilin 2 (Alzheimer Disease 4) (PSEN2) (AA 39-51), (N-Term) antibodyPSEN2 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Presenilin 2 (Alzheimer Disease 4) (PSEN2) (N-Term) antibodyPSEN2 适用: 人, 大鼠, 小鼠, 犬, Cow, 豚鼠, 马, 兔, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Presenilin 2 (Alzheimer Disease 4) (PSEN2) (AA 33-48), (Intracellular) antibodyPSEN2 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Presenilin 2 (Alzheimer Disease 4) (PSEN2) (AA 319-334) antibodyPSEN2 适用: 人, 大鼠 WB, IHC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Presenilin 2 (Alzheimer Disease 4) (PSEN2) (AA 101-150) antibodyPSEN2 适用: 人, 大鼠, 小鼠, 犬, Cow, 豚鼠, 马, 兔, 猴, Bat, Hamster, Pig, 小鸡 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Presenilin 2 (Alzheimer Disease 4) (PSEN2) antibodyPSEN2 适用: 人, 大鼠, 小鼠, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Presenilin 2 (Alzheimer Disease 4) (PSEN2) (AA 32-65), (N-Term) antibodyPSEN2 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB30801 unconjugated
anti-Presenilin 2 (Alzheimer Disease 4) (PSEN2) (AA 7-77) antibodyPSEN2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Presenilin 2 (Alzheimer Disease 4) (PSEN2) (AA 32-65) antibodyPSEN2 适用: 人 WB, IHC, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
IHC-P 1:200-400 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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注意事项
- Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- Presenilin 2 (PSEN2) (Presenilin 2 (Alzheimer Disease 4) (PSEN2))
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别名
- presenilin 2/PS-2
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背景
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Synonyms: AD 3L, AD 3LP, AD 4, AD 5, AD3L, AD3LP, AD4, AD5, Alzheimer disease 4, Alzheimer disease familial type 4, E5 1, Presenilin2, Presenilin 2, Presenilin 2, PS 2, PS2, PSEN 2, PSNL 2, PSNL2, STM 2, STM2.
Background: Alzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1, PSEN2) or the amyloid precursor protein (APP). These disease-linked mutations result in increased production of the longer form of amyloid-beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma-secretase, an enzyme that cleaves APP. Also, it is thought that the presenilins are involved in the cleavage of the Notch receptor, such that they either directly regulate gamma-secretase activity or themselves are protease enzymes. Two alternative transcripts of PSEN2 have been identified.
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基因ID
- 5664
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途径
- Notch Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
抗原
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