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- 抗原 See all SCN5A 抗体
- SCN5A (Sodium Channel, Voltage-Gated, Type V, alpha Subunit (SCN5A))
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抗原表位
- AA 493-511, Intracellular
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适用
- 大鼠
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宿主
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豚鼠
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克隆类型
- 多克隆
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标记
- This SCN5A antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- 原理
- A Guinea Pig Polyclonal Antibody to NaV1.5 (SCN5A) (493-511) Channel
- 特异性
- Intracellular loop between domains I and II
- 交叉反应
- 人, 小鼠, 大鼠
- 预测反应
- Mouse - identical, human - 17,19 amino acid residues identical
- 产品特性
- Guinea pig Anti-NaV1.5 (SCN5A) Antibody , raised in guinea pigs, is a highly specific antibody directed against an epitope of the rat protein. The antibody can be used in western blot and immunohistochemistry applications. It has been designed to recognize NaV1.5 sodium channel from rat, human and mouse samples. The antigen used to immunize guinea pigs is the same as Anti-NaV1.5 (SCN5A) (493-511) Antibody raised in rabbit. Our line of guinea pig antibodies enables more flexibility with our products such as multiplex staining studies, immunoprecipitation, etc.
- 纯化方法
- Affinity purified on immobilized antigen.
- 免疫原
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Immunogen: Synthetic peptide
Immunogen Sequence: DRLPKSDSEDGPRALNQLSC, corresponding to amino acid residues 493-511 of rat NaV1.5
- 亚型
- IgG
- Top Product
- Discover our top product SCN5A Primary Antibody
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anti-Sodium Channel, Voltage-Gated, Type V, alpha Subunit (SCN5A) (Internal Region) antibody
Verified SCN5A 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Sodium Channel, Voltage-Gated, Type V, alpha Subunit (SCN5A) (N-Term) antibodySCN5A 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 斑马鱼, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sodium Channel, Voltage-Gated, Type V, alpha Subunit (SCN5A) antibodySCN5A 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sodium Channel, Voltage-Gated, Type V, alpha Subunit (SCN5A) antibodySCN5A 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sodium Channel, Voltage-Gated, Type V, alpha Subunit (SCN5A) (AA 1856-1905) antibodySCN5A 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 斑马鱼, 猴, Bat, 小鸡, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Sodium Channel, Voltage-Gated, Type V, alpha Subunit (SCN5A) (C-Term) antibodySCN5A 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 斑马鱼, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Sodium Channel, Voltage-Gated, Type V, alpha Subunit (SCN5A) antibodySCN5A 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Sodium Channel, Voltage-Gated, Type V, alpha Subunit (SCN5A) (N-Term) antibodySCN5A 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Sodium Channel, Voltage-Gated, Type V, alpha Subunit (SCN5A) (C-Term) antibodySCN5A 适用: 人, 小鼠, 大鼠, 犬, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sodium Channel, Voltage-Gated, Type V, alpha Subunit (SCN5A) (C-Term) antibodySCN5A 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: N/A
Application Dilutions Western blot wb: 1:200
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- 0.2 mL double distilled water (DDW).
- 浓度
- 1 mg/mL
- 缓冲液
- PBS pH 7.4
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- 抗原
- SCN5A (Sodium Channel, Voltage-Gated, Type V, alpha Subunit (SCN5A))
- 别名
- SCN5A (SCN5A 产品)
- 背景
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Sodium channel protein type 5 subunit alpha, SKM2,Voltage-gated Na+ channels (NaV) are responsible for myocardial conduction and maintenance of the cardiac rhythm and are essential for the generation of action potentials and cell excitability1.Dysfunction or disregulation of cardiac sodium channels can cause several disorders, including cardiac arrhythmias.The majority of Na+ channels in the mammalian heart are Tetrodotoxin (TTX)-insensitive NaV1.52.The putative structure of NaV1.5 consists of four homologous domain (I-IV), each containing six transmembrane segments (S1-S6). Mutations in the C-terminus of NaV1.5 were described in connection to Long QT syndrome and Brugada syndrome1,2. Recent data have demonstrated selective expression of NaV1.5 in the mouse central nervous system and implicated a role for NaV1.5 in the physiology of the central nervous system1.
Alternative names: NaV1.5, Sodium channel protein type 5 subunit alpha, SKM2 - 基因ID
- 25665
- NCBI登录号
- NM_198056
- UniProt
- P15389
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