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Histone 3 抗体 (H3K27me3)

H3 适用: 人, 小鼠 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN703901
发货至: 中国
  • 抗原 See all Histone 3 (H3) 抗体
    Histone 3 (H3)
    抗原表位
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    H3K27me3
    适用
    • 1399
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    人, 小鼠
    宿主
    • 1217
    • 243
    • 8
    • 4
    克隆类型
    • 1120
    • 351
    • 1
    多克隆
    标记
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    This Histone 3 antibody is un-conjugated
    应用范围
    • 1058
    • 410
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    Western Blotting (WB), ELISA, Flow Cytometry (FACS)
    交叉反应
    人, 小鼠
    预测反应
    Rat,Dog,Cow,Sheep,Pig,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic methyl peptide derived from human Histone H3 around methylation site of Lys27
    亚型
    IgG
    Top Product
    Discover our top product H3 Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    Histone 3 (H3)
    别名
    Histone H3 (H3 产品)
    别名
    H-3 antibody, histocompatibility 3 antibody, H3 antibody
    背景

    Synonyms: Histone H3, H3 histone family member E pseudogene, H3F3, HIST3H3, Histone H3 3 pseudogene.

    Background: Modulation of the chromatin structure plays an important role in the regulation of transcription in eukaryotes. The nucleosome, made up of four core histone proteins (H2A, H2B, H3 and H4), is the primary building block of chromatin. The N-terminal tail of core histones undergoes different posttranslational modifications including acetylation, phosphorylation and methylation. These modifications occur in response to cell signal stimuli and have a direct effect on gene expression. In most species, the histone H2B is primarily acetylated at lysines 5, 12, 15 and 20. Histone H3 is primarily acetylated at lysines 9, 14, 18 and 23. Acetylation at lysine 9 appears to have a dominant role in histone deposition and chromatin assembly in some organisms. Phosphorylation at Ser10 of histone H3 is tightly correlated with chromosome condensation during both mitosis and meiosis.

    基因ID
    3020
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