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Paxillin 抗体 (pTyr31) (Cy5.5)

PXN 适用: 小鼠 IF (cc), IF (p) 宿主: 兔 Polyclonal Cy5.5
产品编号 ABIN703516
发货至: 中国
  • 抗原 See all Paxillin (PXN) 抗体
    Paxillin (PXN)
    抗原表位
    • 30
    • 26
    • 17
    • 16
    • 11
    • 9
    • 7
    • 7
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    pTyr31
    适用
    • 188
    • 100
    • 70
    • 15
    • 8
    • 7
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
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    • 1
    小鼠
    宿主
    • 182
    • 22
    • 1
    克隆类型
    • 172
    • 33
    多克隆
    标记
    • 109
    • 10
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 6
    • 6
    • 4
    • 4
    • 4
    • 4
    • 3
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    This Paxillin antibody is conjugated to Cy5.5
    应用范围
    • 154
    • 59
    • 40
    • 39
    • 37
    • 25
    • 22
    • 20
    • 15
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    • 13
    • 6
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    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    特异性
    A mismatch around the phosphorylation site decreases the antibody's affinity in Mouse/Rat samples
    交叉反应
    小鼠
    预测反应
    Human,Rat,Cow,Sheep,Horse,Chicken
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic phosphopeptide derived from human Paxillin around the phosphorylation site of Tyr31
    亚型
    IgG
    Top Product
    Discover our top product PXN Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    Paxillin (PXN)
    别名
    Paxillin (PXN 产品)
    别名
    AW108311 antibody, AW123232 antibody, Pax antibody, CG18061 antibody, CG18576 antibody, CG31794 antibody, CT40481 antibody, CT42454 antibody, DPaxillin antibody, DPxn antibody, DPxn37 antibody, Dmel\\CG31794 antibody, Dpax antibody, DpaxA antibody, PDLP antibody, dPax antibody, pax antibody, wu:fw71f12 antibody, PXN antibody, LOC100220858 antibody, paxillin antibody, Paxillin antibody, paxillin S homeolog antibody, paxillin a antibody, PXN antibody, Pxn antibody, Pax antibody, pxn.S antibody, pxna antibody, LOC696336 antibody, pxn antibody
    背景

    Synonyms: PXNphospho Y31, Paired box protein Pax 1, PAX 1, PAX1, Paxillin alpha, PXN, PXN protein, FLJ16691, FLJ23042, PAXI_HUMAN.

    Background: Paxillin is a 64 kDa cytoskeletal adapter protein involved in organisation and function of focal adhesions, which are critical to cell adhesion and migration. This in turn plays a role in a wide variety of processes including embryogenesis, organogenesis, wound repair, inflammation and cancer. Paxillin contains LD motifs, LIM domains, SH3 and SH2 binding domains that serve as docking sites for cytoskeletal proteins, tyrosine kinases (e.g., FAK, Pyk 2, Src), serine/threonine kinases, GTPase activating proteins and other adaptor proteins (e.g., Actin, Vinculin, Crk).

    基因ID
    5829
    UniProt
    P49023
    途径
    MAPK Pathway, EGFR Signaling Pathway, Response to Growth Hormone Stimulus, Cell-Cell Junction Organization, Maintenance of Protein Location, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
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