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CD80 抗体

CD80 适用: 小鼠, 犬 FACS, IP, IHC (fro), Func 宿主: Armenian Hamster Monoclonal 16-10A1 unconjugated
产品编号 ABIN7013940
发货至: 中国
  • 抗原 See all CD80 抗体
    CD80
    适用
    • 131
    • 94
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    小鼠, 犬
    宿主
    • 87
    • 63
    • 20
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    Armenian Hamster
    克隆类型
    • 116
    • 77
    • 2
    单克隆
    标记
    • 82
    • 16
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    This CD80 antibody is un-conjugated
    应用范围
    • 113
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    Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)
    特异性
    The Armenian hamster monoclonal antibody 16-10A1 reacts with an extracellular epitope of CD80 (B7-1), a 60 kDa single chain type I glycoprotein of immunoglobulin supergene family, expressed on professional antigen-presenting cells, such as dendritic cells, macrophages or activated B lymphocytes.
    纯化方法
    Purified by protein-A affinity chromatography.
    内毒素水平
    Low Endotoxin
    免疫原
    CD80-transfected CHO cell line
    克隆位点
    16-10A1
    亚型
    IgG2
    Top Product
    Discover our top product CD80 Primary Antibody
  • 应用备注
    Flow cytometry: Recommended dilution: 1-4 μg/mL.
    Functional application: Blocking.
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.4
    储存液
    Azide free
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Do not freeze.
  • 抗原
    CD80
    别名
    CD80 (CD80 产品)
    别名
    B7 antibody, B7-1 antibody, B7.1 antibody, BB1 antibody, CD28LG antibody, CD28LG1 antibody, LAB7 antibody, B71 antibody, Cd28l antibody, Ly-53 antibody, Ly53 antibody, MIC17 antibody, TSA1 antibody, CD80 molecule antibody, Cd80 molecule antibody, CD80 antigen antibody, CD80 antibody, Cd80 antibody
    背景
    CD80 Molecule,CD80 (B7-1) and CD86 (B7-2) are ligands of T cell critical costimulatory molecule CD28 and of an inhibitory receptor CTLA-4 (CD152). The both B7 Molecules are expressed on professional antigen-presenting cells and are essential for T cell activation, the both molecules can also substitute for each other in this process. The question what are the differences in CD80 and CD86 competency has not been fully elucidated yet, there are still conflicts in results about their respective roles in initiation or sustaining of the T cell immune response.,B7-1, BB1
    基因ID
    12519
    UniProt
    Q00609
    途径
    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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