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Retinoblastoma 1 抗体 (pSer780)

This anti-Retinoblastoma 1 antibody is a 兔 多克隆 antibody detecting Retinoblastoma 1 in WB. Suitable for 人 和 小鼠.
产品编号 ABIN7265194
发货至: 中国

Quick Overview for Retinoblastoma 1 抗体 (pSer780) (ABIN7265194)

抗原

See all Retinoblastoma 1 (RB1) 抗体
Retinoblastoma 1 (RB1)

适用

  • 244
  • 117
  • 92
  • 5
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  • 3
  • 2
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  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 216
  • 30

克隆类型

  • 194
  • 52
多克隆

标记

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  • 7
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  • 2
  • 2
  • 2
  • 2
  • 2
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  • 2
  • 2
  • 2
  • 2
  • 1
This Retinoblastoma 1 antibody is un-conjugated

应用范围

  • 192
  • 80
  • 79
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  • 65
  • 40
  • 28
  • 27
  • 20
  • 17
  • 12
  • 10
  • 10
  • 8
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  • 6
  • 2
  • 2
Western Blotting (WB)
  • 抗原表位

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    • 5
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    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
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    pSer780

    产品特性

    Phosphorylated antibody

    纯化方法

    Affinity purification

    免疫原

    A phospho specific peptide corresponding to residues surrounding S780 of human RB1

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    Retinoblastoma 1 (RB1)

    别名

    RB1

    背景

    The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

    分子量

    Observed_MW: 100 kDa

    Calculated_MW: 106 kDa

    基因ID

    5925

    UniProt

    P06400

    途径

    Cell Division Cycle, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, DNA Replication, Maintenance of Protein Location, Synthesis of DNA, Autophagy
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