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p53 抗体 (pSer15)

This anti-p53 antibody is a 兔 多克隆 antibody detecting p53 in IF. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7265078
发货至: 中国

Quick Overview for p53 抗体 (pSer15) (ABIN7265078)

抗原

See all p53 (TP53) 抗体
p53 (TP53) (Tumor Protein P53 (TP53))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This p53 antibody is un-conjugated

应用范围

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Immunofluorescence (IF)
  • 抗原表位

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    pSer15

    产品特性

    Phosphorylated antibody

    纯化方法

    Affinity purification

    免疫原

    A synthetic phosphorylated peptide around S15 of human p53 (NP_000537.3).

    亚型

    IgG
  • 应用备注

    IF 1:50-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    p53 (TP53) (Tumor Protein P53 (TP53))

    别名

    p53

    背景

    This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277).

    基因ID

    7157

    UniProt

    P04637

    途径

    p53 Pathway, MAPK Pathway, PI3K-Akt Signaling, Apoptosis, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy, Warburg Effect
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