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ATF2 抗体 (pThr71)

This anti-ATF2 antibody is a 兔 多克隆 antibody detecting ATF2 in IHC 和 IF. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7265028
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for ATF2 抗体 (pThr71) (ABIN7265028)

抗原

See all ATF2 抗体
ATF2 (Activating Transcription Factor 2 (ATF2))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

  • 326
  • 57
多克隆

标记

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This ATF2 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

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    pThr71

    产品特性

    Phosphorylated antibody

    纯化方法

    Affinity purification

    免疫原

    A synthetic phosphorylated peptide around T71 of human ATF2 (NP_001871.2).

    亚型

    IgG
  • 应用备注

    IHC 1:50-1:100 IF 1:50-1:100

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    ATF2 (Activating Transcription Factor 2 (ATF2))

    别名

    ATF2

    背景

    This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro, thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. The encoded protein may also be involved in cell's DNA damage response independent of its role in transcriptional regulation. Several alternatively spliced transcript variants have been found for this gene

    基因ID

    1386

    UniProt

    P15336

    途径

    MAPK Pathway, RTK signaling, Thyroid Hormone Synthesis, Activation of Innate immune Response, Chromatin Binding, Myometrial Relaxation and Contraction, Synaptic Membrane, Tube Formation, Toll-Like Receptors Cascades
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