HLA-DMB 抗体
Quick Overview for HLA-DMB 抗体 (ABIN7252477)
抗原
See all HLA-DMB 抗体适用
宿主
克隆类型
标记
应用范围
-
-
产品特性
- Polyclonal Antibody
-
纯化方法
- Antigen affinity purification
-
免疫原
- Fusion protein of human HLA-DMB
-
亚型
- IgG
-
-
anti-Major Histocompatibility Complex, Class II, DM beta (HLA-DMB) (AA 22-129) antibody
HLA-DMB 适用: 人 WB, ELISA, IF, IP 宿主: 小鼠 Monoclonal 5G11 unconjugated
anti-Major Histocompatibility Complex, Class II, DM beta (HLA-DMB) (AA 40-100) antibodyHLA-DMB 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DM beta (HLA-DMB) (AA 22-129) antibodyHLA-DMB 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 4D12 unconjugated
anti-Major Histocompatibility Complex, Class II, DM beta (HLA-DMB) (AA 22-129) antibodyHLA-DMB 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6B3 unconjugated
anti-Major Histocompatibility Complex, Class II, DM beta (HLA-DMB) (C-Term) antibodyHLA-DMB 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DM beta (HLA-DMB) (AA 81-100), (Middle Region) antibodyHLA-DMB 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DM beta (HLA-DMB) (AA 1-263) antibodyHLA-DMB 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DM beta (HLA-DMB) (C-Term) antibodyHLA-DMB 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DM beta (HLA-DMB) antibodyHLA-DMB 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DM beta (HLA-DMB) (N-Term) antibodyHLA-DMB 适用: 人, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB 1:500-1:2000, IHC 1:30-1:150, ELISA 1:5000-1:10000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1.38 mg/mL
-
缓冲液
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- HLA-DMB (Major Histocompatibility Complex, Class II, DM beta (HLA-DMB))
-
别名
- HLA-DMB
-
背景
- HLA-DMB (Major Histocompatibility Complex, Class II, DM Beta) is a Protein Coding gene. Diseases associated with HLA-DMB include Red-Green Color Blindness and Red Color Blindness. Among its related pathways are ICos-ICosL Pathway in T-Helper Cell and CTLA4 Signaling. GO annotations related to this gene include MHC class II protein complex binding. An important paralog of this gene is ENSG00000248993.HLA-DMB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta (DMB) chain, both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP (class II-associated invariant chain peptide) molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail.
-
分子量
-
Observed_MW: Refer to figures
Calculated_MW: 29 kDa
-
UniProt
- P28068
-
途径
- Cancer Immune Checkpoints, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
抗原
-
