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CHEK2 抗体 (pThr68)

CHEK2 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7250719
发货至: 中国
  • 抗原 See all CHEK2 抗体
    CHEK2 (Checkpoint Kinase 2 (CHEK2))
    抗原表位
    • 29
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    pThr68
    适用
    • 260
    • 95
    • 81
    • 16
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    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 241
    • 20
    • 1
    • 1
    克隆类型
    • 227
    • 36
    多克隆
    标记
    • 115
    • 14
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    This CHEK2 antibody is un-conjugated
    应用范围
    • 205
    • 80
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    • 37
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    • 28
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    • 19
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    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    产品特性
    Phosphorylated antibody
    纯化方法
    Affinity purification
    免疫原
    Synthesized peptide derived from human Chk2 around the phosphorylation site of Thr68
    亚型
    IgG
    Top Product
    Discover our top product CHEK2 Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IHC 1:100-1:300, IF 1:50-1:200, ELISA 1:10000-1:20000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    CHEK2 (Checkpoint Kinase 2 (CHEK2))
    别名
    CHEK2 (CHEK2 产品)
    别名
    CDS1 antibody, CHK2 antibody, HuCds1 antibody, LFS2 antibody, PP1425 antibody, RAD53 antibody, hCds1 antibody, fa66f08 antibody, wu:fa66f08 antibody, zgc:55865 antibody, Cds1 antibody, HUCDS1 antibody, Rad53 antibody, Chk2 antibody, cds1 antibody, chek2 antibody, chk2 antibody, hucds1 antibody, lfs2 antibody, pp1425 antibody, rad53 antibody, checkpoint kinase 2 antibody, serine/threonine-protein kinase chk2 antibody, checkpoint kinase 2 L homeolog antibody, CHEK2 antibody, chek2 antibody, Chek2 antibody, MCYG_07308 antibody, chek2.L antibody
    背景
    Regulates cell cycle checkpoints and apoptosis in response to DNA damage, particularly to DNA double-strand breaks. Inhibits CDC25C phosphatase by phosphorylation on 'Ser-216', preventing the entry into mitosis. May also play a role in meiosis. Regulates the TP53 tumor suppressor through phosphorylation at 'Thr-18' and 'Ser-20'.
    分子量

    Observed_MW: 61 kDa

    Calculated_MW: 61 kDa

    UniProt
    O96017
    途径
    p53 Pathway, Apoptosis, Cell Division Cycle
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