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HDAC1 抗体
HDAC1
适用: 人, 小鼠, 大鼠
IHC (p)
宿主: 小鼠
Monoclonal
4E1
unconjugated
HDAC1抗体详情
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抗原
See all HDAC1 抗体
HDAC1
(Histone Deacetylase 1 (HDAC1))
适用
All reactivities for HDAC1 抗体
人, 小鼠, 大鼠
宿主
All hosts for HDAC1 抗体
小鼠
克隆类型
All clonalities for HDAC1 抗体
单克隆
标记
All conjugates for HDAC1 抗体
This HDAC1 antibody is un-conjugated
应用范围
All applications for HDAC1 抗体
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
产品特性
Monoclonal Antibody
纯化方法
Protein A purification
免疫原
Synthetic Peptide of HDAC1
克隆位点
4E1
亚型
IgG
Top Product
Discover our top product HDAC1 Primary Antibody
Alternatives
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anti-Histone Deacetylase 1 (HDAC1) (Middle Region) antibody
HDAC1
适用: 人, 小鼠, 大鼠, 兔, Cow, 犬, 豚鼠, 马, 斑马鱼, Saccharomyces cerevisiae
WB, IHC
宿主: 兔
Polyclonal
unconjugated
使用细节
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应用备注
IHC 1:100-200
限制
仅限研究用
贮存及处理
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状态
Liquid
浓度
1 mg/mL
缓冲液
PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
Store at -20°C. Avoid freeze / thaw cycles.
HDAC1目标详情
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抗原
HDAC1
(Histone Deacetylase 1 (HDAC1))
别名
HDAC1 (HDAC1 产品 )
别名
GON-10 antibody, HD1 antibody, RPD3 antibody, RPD3L1 antibody, CG7471 antibody, DHDAC1 antibody, DRpd3 antibody, DmHDAC1 antibody, Dmel\\CG7471 antibody, E(var)3-64BC antibody, HDAC antibody, HDAC-1 antibody, HDAC1 antibody, Hdac1 antibody, Rpd3/HDAC antibody, Su(var)3-26 antibody, Su(var)326 antibody, Su(var)328 antibody, dHDAC-1 antibody, dHDAC1 antibody, dRPD3 antibody, dRpd3 antibody, dmHDA401 antibody, drpd3 antibody, hdac1 antibody, l(3)04556 antibody, l(3)64Cc antibody, rpd3 antibody, rpd[3] antibody, gon-10 antibody, hdac1b antibody, rpd3l1 antibody, Rpd3 antibody, GB14706 antibody, hdac1-b antibody, chunp6919 antibody, hdac-1 antibody, mp:zf637-2-001987 antibody, wu:fb19h11 antibody, wu:fi06f03 antibody, zgc:101582 antibody, zgc:65818 antibody, Hdac1-ps antibody, MommeD5 antibody, ARABIDOPSIS HISTONE DEACETYLASE 1 antibody, ARABIDOPSIS HISTONE DEACETYLASE 19 antibody, ATHD1 antibody, ATHDA19 antibody, ATRPD3A antibody, F20D10.250 antibody, F20D10_250 antibody, HDA1 antibody, HDA19 antibody, HISTONE DEACETYLASE antibody, HISTONE DEACETYLASE 19 antibody, HISTONE DEACETYLASE19 antibody, RPD3A antibody, histone deacetylase 1 antibody, HDM antibody, ab21 antibody, hdac1a antibody, histone deacetylase 1 antibody, Histone deacetylase 1 antibody, histone deacetylase antibody, histone deacetylase 1 S homeolog antibody, histone deacetylase Rpd3 antibody, histone deacetylase 1 L homeolog antibody, HDAC1 antibody, hdac1.S antibody, LOC411503 antibody, hdac1 antibody, Hdac1 antibody, HD1 antibody, hda-1 antibody, hdac1.L antibody, LOC748850 antibody
背景
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Deacetylates SP proteins, SP1 and SP3, and regulates their function. Component of the BRG1-RB1-HDAC1 complex, which negatively regulates the CREST-mediated transcription in resting neurons. Upon calcium stimulation, HDAC1 is released from the complex and CREBBP is recruited, which facilitates transcriptional activation. Deacetylates TSHZ3 and regulates its transcriptional repressor activity. Deacetylates 'Lys-310' in RELA and thereby inhibits the transcriptional activity of NF-kappa-B.
UniProt
Q13547
途径
Neurotrophin Signaling Pathway , Intracellular Steroid Hormone Receptor Signaling Pathway , Regulation of Intracellular Steroid Hormone Receptor Signaling , Mitotic G1-G1/S Phases , Regulation of Muscle Cell Differentiation , Skeletal Muscle Fiber Development , Negative Regulation of intrinsic apoptotic Signaling , Embryonic Body Morphogenesis
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