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HDAC1 抗体

HDAC1 适用: 人, 小鼠, 大鼠 IHC (p) 宿主: 小鼠 Monoclonal 4E1 unconjugated
产品编号 ABIN7250531
发货至: 中国
  • 抗原 See all HDAC1 抗体
    HDAC1 (Histone Deacetylase 1 (HDAC1))
    适用
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    人, 小鼠, 大鼠
    宿主
    • 139
    • 22
    • 2
    小鼠
    克隆类型
    • 140
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    单克隆
    标记
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    This HDAC1 antibody is un-conjugated
    应用范围
    • 117
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    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    产品特性
    Monoclonal Antibody
    纯化方法
    Protein A purification
    免疫原
    Synthetic Peptide of HDAC1
    克隆位点
    4E1
    亚型
    IgG
    Top Product
    Discover our top product HDAC1 Primary Antibody
  • 应用备注
    IHC 1:100-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    HDAC1 (Histone Deacetylase 1 (HDAC1))
    别名
    HDAC1 (HDAC1 产品)
    别名
    GON-10 antibody, HD1 antibody, RPD3 antibody, RPD3L1 antibody, CG7471 antibody, DHDAC1 antibody, DRpd3 antibody, DmHDAC1 antibody, Dmel\\CG7471 antibody, E(var)3-64BC antibody, HDAC antibody, HDAC-1 antibody, HDAC1 antibody, Hdac1 antibody, Rpd3/HDAC antibody, Su(var)3-26 antibody, Su(var)326 antibody, Su(var)328 antibody, dHDAC-1 antibody, dHDAC1 antibody, dRPD3 antibody, dRpd3 antibody, dmHDA401 antibody, drpd3 antibody, hdac1 antibody, l(3)04556 antibody, l(3)64Cc antibody, rpd3 antibody, rpd[3] antibody, gon-10 antibody, hdac1b antibody, rpd3l1 antibody, Rpd3 antibody, GB14706 antibody, hdac1-b antibody, chunp6919 antibody, hdac-1 antibody, mp:zf637-2-001987 antibody, wu:fb19h11 antibody, wu:fi06f03 antibody, zgc:101582 antibody, zgc:65818 antibody, Hdac1-ps antibody, MommeD5 antibody, ARABIDOPSIS HISTONE DEACETYLASE 1 antibody, ARABIDOPSIS HISTONE DEACETYLASE 19 antibody, ATHD1 antibody, ATHDA19 antibody, ATRPD3A antibody, F20D10.250 antibody, F20D10_250 antibody, HDA1 antibody, HDA19 antibody, HISTONE DEACETYLASE antibody, HISTONE DEACETYLASE 19 antibody, HISTONE DEACETYLASE19 antibody, RPD3A antibody, histone deacetylase 1 antibody, HDM antibody, ab21 antibody, hdac1a antibody, histone deacetylase 1 antibody, Histone deacetylase 1 antibody, histone deacetylase antibody, histone deacetylase 1 S homeolog antibody, histone deacetylase Rpd3 antibody, histone deacetylase 1 L homeolog antibody, HDAC1 antibody, hdac1.S antibody, LOC411503 antibody, hdac1 antibody, Hdac1 antibody, HD1 antibody, hda-1 antibody, hdac1.L antibody, LOC748850 antibody
    背景
    Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Deacetylates SP proteins, SP1 and SP3, and regulates their function. Component of the BRG1-RB1-HDAC1 complex, which negatively regulates the CREST-mediated transcription in resting neurons. Upon calcium stimulation, HDAC1 is released from the complex and CREBBP is recruited, which facilitates transcriptional activation. Deacetylates TSHZ3 and regulates its transcriptional repressor activity. Deacetylates 'Lys-310' in RELA and thereby inhibits the transcriptional activity of NF-kappa-B.
    UniProt
    Q13547
    途径
    Neurotrophin Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Mitotic G1-G1/S Phases, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Negative Regulation of intrinsic apoptotic Signaling, Embryonic Body Morphogenesis
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