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- 抗原 See all MC1 Receptor (MC1R) 抗体
- MC1 Receptor (MC1R) (Melanocortin 1 Receptor (MC1R))
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MC1 Receptor antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC)
- 产品特性
- Polyclonal Antibody
- 纯化方法
- Affinity purification
- 免疫原
- Synthetic peptide of human MC1R
- 亚型
- IgG
- Top Product
- Discover our top product MC1R Primary Antibody
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anti-Melanocortin 1 Receptor (MC1R) (AA 1-37) antibody
MC1R 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Melanocortin 1 Receptor (MC1R) (AA 271-317) antibodyMC1R 适用: 人, 小鼠 WB, ELISA, IF (cc), IF (p), FACS, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Melanocortin 1 Receptor (MC1R) (C-Term) antibodyMC1R 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Melanocortin 1 Receptor (MC1R) (C-Term) antibodyMC1R 适用: 人 WB, IF, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Melanocortin 1 Receptor (MC1R) (3rd Intracellular Loop), (AA 217-232) antibodyMC1R 适用: 人, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Melanocortin 1 Receptor (MC1R) (Cytoplasmic Domain) antibodyMC1R 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Melanocortin 1 Receptor (MC1R) (AA 271-317) antibody (Alexa Fluor 488)MC1R 适用: 人, 小鼠 WB, IF (cc), IF (p), FACS 宿主: 兔 Polyclonal Alexa Fluor 488
anti-Melanocortin 1 Receptor (MC1R) (C-Term) antibodyMC1R 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Melanocortin 1 Receptor (MC1R) (AA 1-80) antibodyMC1R 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- IHC 1:50-1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.9 mg/mL
- 缓冲液
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- MC1 Receptor (MC1R) (Melanocortin 1 Receptor (MC1R))
- 别名
- MC1R (MC1R 产品)
- 别名
- CMM5 antibody, MSH-R antibody, SHEP2 antibody, Mshra antibody, Tob antibody, e antibody, MC1-R antibody, MSHR antibody, mc1r antibody, MC1R antibody, TUBB3 antibody, melanocortin 1 receptor antibody, melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) antibody, MC1R antibody, Mc1r antibody, mc1r antibody, mc1r_par1 antibody
- 背景
- This intronless gene encodes the receptor protein for melanocyte-stimulating hormone (MSH). The encoded protein, a seven pass transmembrane G protein coupled receptor, controls melanogenesis. Two types of melanin exist: red pheomelanin and black eumelanin. Gene mutations that lead to a loss in function are associated with increased pheomelanin production, which leads to lighter skin and hair color. Eumelanin is photoprotective but pheomelanin may contribute to UV-induced skin damage by generating free radicals upon UV radiation. Binding of MSH to its receptor activates the receptor and stimulates eumelanin synthesis. This receptor is a major determining factor in sun sensitivity and is a genetic risk factor for melanoma and non-melanoma skin cancer. Over 30 variant alleles have been identified which correlate with skin and hair color, providing evidence that this gene is an important component in determining normal human pigment variation.
- NCBI登录号
- NP_002377
- UniProt
- Q01726
- 途径
- cAMP Metabolic Process, Feeding Behaviour
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