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EID1 抗体

EID1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7241222
发货至: 中国
  • 抗原 See all EID1 抗体
    EID1 (EP300 Interacting Inhibitor of Differentiation 1 (EID1))
    适用
    • 22
    • 9
    • 1
    • 1
    宿主
    • 15
    • 7
    克隆类型
    • 18
    • 4
    多克隆
    标记
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This EID1 antibody is un-conjugated
    应用范围
    • 15
    • 12
    • 10
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    产品特性
    Polyclonal Antibody
    纯化方法
    Affinity purification
    免疫原
    Recombinant protein of human EID1
    亚型
    IgG
    Top Product
    Discover our top product EID1 Primary Antibody
  • 应用备注
    IHC 1:50-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.6 mg/mL
    缓冲液
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    EID1 (EP300 Interacting Inhibitor of Differentiation 1 (EID1))
    别名
    EID1 (EID1 产品)
    别名
    C15orf3 antibody, CRI1 antibody, EID-1 antibody, IRO45620 antibody, PTD014 antibody, RBP21 antibody, 2610002K20Rik antibody, Cri1 antibody, ORF12 antibody, PNAS-22 antibody, RGD1562702 antibody, EP300 interacting inhibitor of differentiation 1 antibody, EID1 antibody, Eid1 antibody
    背景
    E1A-like inhibitor of differentiation-1 (EID-1), an acetyltransferase enzyme, binds both the retinoblastoma protein (Rb), a regulator of cell cycle and tissue specific transcription, and the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. EID-1 inhibits cellular differentiation by blocking the histone acetyltransferase activity of p300. EID-1 also acetylates both histones and non-histone proteins such as NCOA3 co-activator. By acetylating histones, EID-1 gives a specific tag for transcriptional activation. In addition to binding Rb and p300, EID-1 also binds to phosphorylated CREB protein, mediating cAMP gene regulation. EID-1 augments the activity of phosphorylated CREB and activates transcription of cAMP responsive genes as a co-activator.
    NCBI登录号
    NP_055150
    UniProt
    Q9Y6B2
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