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- 抗原 See all HMGB4 抗体
- HMGB4 (High Mobility Group Box 4 (HMGB4))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HMGB4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 产品特性
- Polyclonal Antibody
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant protein of human HMGB4
- 亚型
- IgG
- Top Product
- Discover our top product HMGB4 Primary Antibody
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anti-High Mobility Group Box 4 (HMGB4) (AA 31-130) antibody
HMGB4 适用: 人, 大鼠, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-High Mobility Group Box 4 (HMGB4) (AA 25-167) antibodyHMGB4 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-High Mobility Group Box 4 (HMGB4) (AA 1-186) antibodyHMGB4 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-High Mobility Group Box 4 (HMGB4) (N-Term) antibodyHMGB4 适用: 人, 大鼠, 小鼠 WB, ICC 宿主: 兔 Polyclonal unconjugated
anti-High Mobility Group Box 4 (HMGB4) (C-Term) antibodyHMGB4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-High Mobility Group Box 4 (HMGB4) (AA 6-173) antibodyHMGB4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-High Mobility Group Box 4 (HMGB4) (N-Term) antibodyHMGB4 适用: 人, 大鼠, 小鼠, Cow, 豚鼠, 马, Pig, 兔, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-High Mobility Group Box 4 (HMGB4) (AA 45-73) antibodyHMGB4 适用: 人, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:200-1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.2 mg/mL
- 缓冲液
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- HMGB4 (High Mobility Group Box 4 (HMGB4))
- 别名
- HMGB4 (HMGB4 产品)
- 别名
- HMGB4 antibody, dJ1007G16.5 antibody, 1700001F22Rik antibody, AI326135 antibody, high mobility group box 4 antibody, high-mobility group box 4 antibody, HMGB4 antibody, Hmgb4 antibody
- 背景
- High mobility group protein B4is atranscription factorthat in humans is encoded by theHMGB4gene.HMGB4 is strongly and preferentially expressed in the adult mouse testis and weakly in the brain, but not in many other tissues. HMGB4 associates with chromatin, and in transfection assays, in contrast to HMGB1, it acts as a potent transcriptional repressor. During spermatogenesis, HMGB4 is present in the euchromatin of late pachytene spermatocytes and haploid round spermatids, whereas stronger expression is observed during the elongation phase, where it localizes to the basal pole of the nucleus in a manner mutually exclusive with H1FNT (H1T2) localized at the apical pole. HMGB4 basal localization is lost in H1FNT-mutant spermatids, showing that H1FNT provides a positional cue for organizing chromatin domains within the nucleus. These results show that HMGB4 and H1FNT specify distinct chromatin domains at the apical and basal poles of the elongating spermatid nucleus.
- 分子量
- 22 kDa
- UniProt
- Q8WW32
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