LAMTOR1 抗体 (N-Term)
LAMTOR1
适用: 人, 小鼠, 大鼠
WB, IF, ELISA, IHC (p)
宿主: 兔
Polyclonal
unconjugated
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- 抗原 See all LAMTOR1 抗体
- LAMTOR1 (Late Endosomal/lysosomal Adaptor, MAPK and mTOR Activator 1 (LAMTOR1))
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抗原表位
- N-Term
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This LAMTOR1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- LAMTOR1 antibody is human, mouse and rat specific. LAMTOR1 antibody is predicted to not cross-react with other LAMTOR family proteins.
- 纯化方法
- LAMTOR1 antibody is affinity chromatography purified via peptide column.
- 免疫原
- Rabbit polyclonal LAMTOR1 antibody was raised against a 17 amino acid peptide near the amino terminus of human LAMTOR1 . The immunogen is located within the first 50 amino acids of LAMTOR1.
- 亚型
- IgG
- Top Product
- Discover our top product LAMTOR1 Primary Antibody
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anti-Late Endosomal/lysosomal Adaptor, MAPK and mTOR Activator 1 (LAMTOR1) (AA 1-161) antibody
LAMTOR1 适用: 人 WB, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Late Endosomal/lysosomal Adaptor, MAPK and mTOR Activator 1 (LAMTOR1) (AA 2-161) antibodyLAMTOR1 适用: 人 IF, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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LAMTOR1 antibody can be used for detection of LAMTOR1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- LAMTOR1 antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,4 °C
- 储存方法
- LAMTOR1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- 抗原
- LAMTOR1 (Late Endosomal/lysosomal Adaptor, MAPK and mTOR Activator 1 (LAMTOR1))
- 别名
- LAMTOR1 (LAMTOR1 产品)
- 别名
- C11orf59 antibody, PDRO antibody, Ragulator1 antibody, p18 antibody, p27RF-Rho antibody, 2400001E08Rik antibody, Pdro antibody, C15H11orf59 antibody, c11orf59 antibody, flj20625 antibody, p27rf-rho antibody, pdro antibody, ragulator1 antibody, late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 antibody, late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 S homeolog antibody, LAMTOR1 antibody, Lamtor1 antibody, lamtor1.S antibody
- 背景
- LAMTOR1 is a 161 amino acid membrane protein belonging to the LAMTOR family. It has been identified to interact with and recruit the four Rag GTPases (Rag A-D) to the surface of lysosomes (1). The mTORC1 kinase complex is a critical component in the regulation of cell growth (2). As part of the ragulator complex, LAMTOR1 recruits the Rag GTPases and the mTORC1 complex to lysosomes, a key step in activation of the TOR signaling cascade by amino acids (3). LAMTOR1 may be involved in cholesterol homeostasis regulating LDL uptake and cholesterol release from late endosomes / lysosomes (4).
- 分子量
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Predicted: 18 kDa
Observed: 18 kDa - 基因ID
- 55004
- NCBI登录号
- NP_060377
- UniProt
- Q6IAA8
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