ZGPAT 抗体 (C-Term)
-
- 抗原 See all ZGPAT 抗体
- ZGPAT (Zinc Finger, CCCH-Type with G Patch Domain (ZGPAT))
-
抗原表位
- C-Term
-
适用
- 人
-
宿主
-
小鸡
-
克隆类型
- 多克隆
-
标记
- This ZGPAT antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF)
- 特异性
- Multiple isoforms of ZGPAT are known to exist.
- 纯化方法
- ZGPAT Antibody is affinity chromatography purified via peptide column.
- 免疫原
- ZGPAT antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human ZGPAT. The immunogen is located within the last 50 amino acids of ZGPAT.
- 亚型
- IgY
- Top Product
- Discover our top product ZGPAT Primary Antibody
-
anti-Zinc Finger, CCCH-Type with G Patch Domain (ZGPAT) (AA 254-303) antibody
ZGPAT 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger, CCCH-Type with G Patch Domain (ZGPAT) (N-Term) antibodyZGPAT 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 绵羊 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger, CCCH-Type with G Patch Domain (ZGPAT) (C-Term) antibodyZGPAT 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 绵羊, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger, CCCH-Type with G Patch Domain (ZGPAT) antibodyZGPAT 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger, CCCH-Type with G Patch Domain (ZGPAT) antibodyZGPAT 适用: 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger, CCCH-Type with G Patch Domain (ZGPAT) (C-Term) antibodyZGPAT 适用: 人, 小鼠, 大鼠, 马, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger, CCCH-Type with G Patch Domain (ZGPAT) (C-Term) antibodyZGPAT 适用: 人 WB, ELISA, IHC, IHC (p), IF 宿主: 小鸡 Polyclonal unconjugated
anti-Zinc Finger, CCCH-Type with G Patch Domain (ZGPAT) (N-Term) antibodyZGPAT 适用: 人, 小鼠, 大鼠, 犬, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger, CCCH-Type with G Patch Domain (ZGPAT) (AA 212-511) antibodyZGPAT 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger, CCCH-Type with G Patch Domain (ZGPAT) (C-Term) antibodyZGPAT 适用: 人 WB, IF, EIA 宿主: 小鸡 Polyclonal unconjugated
-
- 应用备注
-
ZGPAT antibody can be used for detection of ZGPAT by Western blot at 1 μ,g/mL. Antibody can also be used for immunofluorescence starting at 20 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. - 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- ZGPAT Antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,4 °C
- 储存方法
- ZGPAT antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
-
- 抗原
- ZGPAT (Zinc Finger, CCCH-Type with G Patch Domain (ZGPAT))
- 别名
- ZGPAT (ZGPAT 产品)
- 别名
- zc3h9 antibody, gpatc6 antibody, gpatch6 antibody, zc3hdc9 antibody, GPATC6 antibody, GPATCH6 antibody, KIAA1847 antibody, ZC3H9 antibody, ZC3HDC9 antibody, ZIP antibody, 1500006I01Rik antibody, BC021513 antibody, RGD1310801 antibody, zgc:63730 antibody, zinc finger CCCH-type and G-patch domain containing antibody, zinc finger, CCCH-type with G-patch domain L homeolog antibody, zinc finger, CCCH-type with G-patch domain antibody, zinc finger, CCCH-type with G patch domain antibody, ZGPAT antibody, zgpat.L antibody, zgpat antibody, Zgpat antibody
- 背景
- ZGPAT Antibody: The Zinc finger CCCH-type with G patch domain-containing protein (ZGPAT), is a transcriptional repressor that regulates several cellular pathways including EGFR pathways that are involved in cell proliferation, migration and survival. ZGPAT recruits the Mi-2/NuRD complex and represses the expression of EGFR. ZGPAT is down-regulated in breast carcinomas and its expression is negatively correlated with that of EGFR, suggesting that it may be a potential target for breast cancer therapy. Multiple isoforms of ZGPAT are known to exist, including sZIP, which binds to the Mi-2/NuRD complex but lacks the DNA binding component of full-length ZGPAT, thereby antagonizing transcription repression and growth inhibition by ZGPAT.
- 基因ID
- 84619
- NCBI登录号
- NP_115916
- UniProt
- Q8N5A5
- 途径
- EGFR Signaling Pathway
-
