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ZGPAT 抗体 (C-Term)

ZGPAT 适用: 人 WB, IF, EIA 宿主: 小鸡 Polyclonal unconjugated
产品编号 ABIN1450081
发货至: 中国
  • 抗原 See all ZGPAT 抗体
    ZGPAT (Zinc Finger, CCCH-Type with G Patch Domain (ZGPAT))
    抗原表位
    • 15
    • 5
    • 2
    • 1
    • 1
    C-Term
    适用
    • 25
    • 19
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    宿主
    • 24
    • 2
    小鸡
    克隆类型
    • 26
    多克隆
    标记
    • 12
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ZGPAT antibody is un-conjugated
    应用范围
    • 25
    • 13
    • 13
    • 7
    • 6
    • 5
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    交叉反应 (详细)
    Species reactivity (tested):Human.
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    15 amino acid synthetic peptide near the carboxy terminus of human ZGPAT
    Top Product
    Discover our top product ZGPAT Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 0.02 % Sodium Azide as preservative
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    ZGPAT (Zinc Finger, CCCH-Type with G Patch Domain (ZGPAT))
    别名
    ZGPAT (ZGPAT 产品)
    背景
    The Zinc finger CCCH-type with G patch domain-containing protein (ZGPAT), is a transcriptional repressor that regulates several cellular pathways including EGFR pathways that are involved in cell proliferation, migration and survival. ZGPAT recruits the Mi-2/NuRD complex and represses the expression of EGFR. ZGPAT is down-regulated in breast carcinomas and its expression is negatively correlated with that of EGFR, suggesting that it may be a potential target for breast cancer therapy. Multiple isoforms of ZGPAT are known to exist, including sZIP, which binds to the Mi-2/NuRD complex but lacks the DNA binding component of full-length ZGPAT, thereby antagonizing transcription repression and growth inhibition by ZGPAT.Synonyms: G patch domain-containing protein 6, GPATC6, GPATCH6, KIAA1847, ZC3H9, ZC3HDC9, Zinc finger CCCH domain-containing protein 9, Zinc finger CCCH-type with G patch domain-containing protein
    基因ID
    84619
    NCBI登录号
    NP_115916
    途径
    EGFR Signaling Pathway
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