SLUG 抗体 (AA 70-120)
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- 抗原 See all SLUG products
- SLUG
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抗原表位
- AA 70-120
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SLUG antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 纯化方法
- Slug Antibody is affinity chromatography purified via peptide column.
- 免疫原
- Slug antibody was raised against a 14 amino acid synthetic peptide from near the center of human Slug. The immunogen is located within amino acids 70 - 120 of Slug.
- 亚型
- IgG
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anti-SLUG (AA 98-129) antibody
适用: 人, 大鼠, 小鼠 WB, IHC (p), IF 宿主: 兔 Polyclonal RB01398 unconjugated
anti-SLUG (AA 5-120) antibody适用: 人, 大鼠, 兔 WB, IF (cc), IF (p), ELISA, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-SLUG antibody适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-SLUG (AA 1-30), (N-Term) antibody适用: 人 WB 宿主: 兔 Polyclonal RB15389 unconjugated
anti-SLUG (Middle Region 2) antibody适用: 人, 小鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Slug antibody can be used for detection of Slug by Western blot at 1 to 2 μ,g/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Slug Antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,4 °C
- 储存方法
- Slug antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- 抗原
- SLUG
- Abstract
- SLUG 产品
- 别名
- Slug antibody, Slugh antibody, Snail2 antibody, SLUG antibody, SLUGH antibody, SLUGH1 antibody, SNAIL2 antibody, WS2D antibody, snail family zinc finger 2 antibody, snail family transcriptional repressor 2 antibody, Snai2 antibody, SNAI2 antibody
- 背景
- Slug Antibody: Slug, a member of the Snail family of C2H2-type zinc finger transcription factors, was initially identified to be involved in epithelial-mesenchymal transitions as well as the formation of the neural tube during vertebrate embryogenesis. Like Snail, Slug transcription can be induced by growth factors such as FGF, BMP, and TGF-beta. Once expressed, Slug will bind E-box regions of promoters and repress transcription of genes such as E-cadherin and Claudin-1. More recently, its expression in breast, esophogeal, and colorectal carcinomas has been correlated with poor prognosis for survival. Furthermore, Slug can protect hemapoietic progenitor cells from radiation-induced apoptosis by repressing the p53-mediated transcription of Puma, a BH3-only antagonist of the anti-apoptotic members of the Bcl-2 family. Slug antibody has no cross-reactivity to Snail protein.
- 基因ID
- 6591
- UniProt
- O43623
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