DIABLO 抗体 (C-Term)
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- 抗原 See all DIABLO 抗体
- DIABLO (Second Mitochondria-Derived Activator of Caspase (DIABLO))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DIABLO antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)
- 纯化方法
- Smac Antibody is affinity chromatography purified via peptide column.
- 免疫原
- Anti-Smac antibody was raised against a peptide corresponding to 15 amino acids near the carboxy terminus of human Smac. The immunogen is located within the last 50 amino acids of Smac.
- 亚型
- IgG
- Top Product
- Discover our top product DIABLO Primary Antibody
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anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) (AA 211-239), (C-Term) antibody
DIABLO 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB20755 unconjugated
anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) (AA 1-232) antibodyDIABLO 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) antibodyDIABLO 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) (AA 131-239) antibodyDIABLO 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) antibodyDIABLO 适用: 人, 猴 WB, IHC (p) 宿主: 小鼠 Monoclonal 79-1-83 unconjugated
anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) (AA 56-239) antibodyDIABLO 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) antibodyDIABLO 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) (AA 168-236) antibodyDIABLO 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) (AA 1-239) antibodyDIABLO 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) (C-Term) antibodyDIABLO 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB: 1 μ,g/mL, IHC: 5 μ,g/mL.
Antibody validated: Western Blot in human, mouse and rat samples, Immunohistochemistry in human samples. All other applications and species not yet tested. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Smac Antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,4 °C
- 储存方法
- Smac antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- 抗原
- DIABLO (Second Mitochondria-Derived Activator of Caspase (DIABLO))
- 别名
- Smac (DIABLO 产品)
- 别名
- smac antibody, smac3 antibody, diablo-s antibody, 0610041G12Rik antibody, 1700006L01Rik antibody, AU040403 antibody, Smac antibody, DFNA64 antibody, SMAC antibody, DBO antibody, XSmac antibody, diablo, IAP-binding mitochondrial protein antibody, diablo IAP-binding mitochondrial protein antibody, diablo, IAP-binding mitochondrial protein L homeolog antibody, diablo antibody, Diablo antibody, DIABLO antibody, diablo.L antibody
- 背景
- Smac Antibody: The inhibitor of apoptosis proteins (IAPs) regulate programmed cell death by inhibiting members of the caspase family of enzymes. A novel mammalian protein that binds to IAPs and neutralizes the inhibitory effect of IAPs on caspases was recently identified and designated Smac/DIABLO. Smac/DIABLO is a mitochondrial protein that is released along with cytochrome c during apoptosis and activates cytochrome c/Apaf-1/capase-9 pathway. Analysis of the structural basis of Smac/DIABLO reveals that the N-terminal amino acids are required for binding of Smac/DIABLO to IAPs and activation of caspases. Smac/DIABLO is expressed in a variety of human and mouse tissues.
- 分子量
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Predicted: 27kD
Observed: 20 kD kDa - 基因ID
- 66593
- NCBI登录号
- NP_063940
- UniProt
- Q9JIQ3
- 途径
- Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
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