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BAX 抗体 (N-Term)

Name: BAX 抗体 (N-Term)
Brand: antibodies-online
SKU: ABIN6990475
Availability: OutOfStock

BAX 适用: 人 WB, ELISA, IF, IP, ICC 宿主: 兔 Polyclonal unconjugated

(1 reference)

产品编号 ABIN6990475

发货至: 中国

Datasheet as PDF

抗原 See all BAX 抗体

BAX (BCL2-Associated X Protein (BAX))
抗原表位
36

32

18

17

15

11

10

10

9

8

8

7

6

5

4

4

3

3

3

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
N-Term
适用
252

153

142

46

31

27

25

18

17

10

9

5

3

3

3

2

1

1

1

1

1
人
宿主
165

94

3

2
兔
Compatible Secondaries
克隆类型
179

85
多克隆
标记
136

16

13

12

10

7

5

5

5

5

5

5

5

5

5

5

5

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This BAX antibody is un-conjugated
应用范围
237

110

72

64

52

52

51

41

37

12

12

8

5

3

1

1

1

1

1

1

1

1

1
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC)

纯化方法

Bax Antibody is Ion exchange chromatography purified.

免疫原

Bax antibody was raised against a peptide corresponding to 16 amino acids near the amino-terminus of human Bax. The immunogen is located within the first 50 amino acids of Bax.

亚型

IgG

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anti-BCL2-Associated X Protein (BAX) (AA 13-160) antibody
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BAX 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal RB0952 unconjugated

应用备注

Bax antibody can be used for detection of Bax by Western blot at 1 to 4 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 2 μ,g/mL. For immunofluorescence start at 2 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

Bax Antibody is supplied in PBS containing 0.02 % sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C,4 °C

储存方法

Bax antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Tvrdá, Ďuračka, Benko, Kováčik, Lovíšek, Gálová, Žiarovská, Schwarzová, Kačániová: "Ejaculatory Abstinence Affects the Sperm Quality in Normozoospermic Men-How Does the Seminal Bacteriome Respond?" in: International journal of molecular sciences, Vol. 24, Issue 4, (2023) (PubMed).
抗原

BAX (BCL2-Associated X Protein (BAX))

别名

Bax (BAX 产品)

别名

BAX-ALPHA antibody, bax-A antibody, xBax antibody, xlbax antibody, BAX antibody, bax antibody, fj16e01 antibody, wu:fc50b10 antibody, wu:fj16e01 antibody, BCL2L4 antibody, zgc:112983 antibody, BCL2 associated X, apoptosis regulator antibody, BCL2-associated X protein L homeolog antibody, BCL2-associated X protein antibody, bcl2-associated X protein, a antibody, bcl2-associated X protein, b antibody, BAX antibody, bax.L antibody, bax antibody, baxa antibody, Bax antibody, baxb antibody

背景

Bax Antibody: Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death. Bax, a pro-apoptotic Bcl-2 family member, is a cytosolic protein that changes conformation and translocates to the mitochondria following apoptotic stimuli. It is thought to share significant functional homology with Bak, another pro-apoptotic Bcl-2 family member, as disruption of bax or bak has little effect on cell death, but mice lacking both genes display multiple developmental defects and cells lacking both show decreased apoptotic capability.

基因ID

581

UniProt

Q07812

途径

p53 Pathway, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response