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NAIP 抗体 (C-Term)

NAIP 适用: 人 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6990465
发货至: 中国
  • 抗原 See all NAIP 抗体
    NAIP (NLR Family, Apoptosis Inhibitory Protein (NAIP))
    抗原表位
    • 15
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1200-1250, C-Term
    适用
    • 31
    • 4
    • 2
    宿主
    • 31
    • 1
    • 1
    克隆类型
    • 31
    • 2
    多克隆
    标记
    • 16
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NAIP antibody is un-conjugated
    应用范围
    • 26
    • 13
    • 13
    • 13
    • 8
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
    特异性
    Minor, lower molecular weight bands may represent alternately spliced forms.
    纯化方法
    NAIP Antibody is affinity chromatography purified via peptide column.
    免疫原
    NAIP antibody was raised against a synthetic peptide corresponding to 13 amino acids at the C-terminus of human NAIP. The immunogen is located within amino acids 1200 - 1250 of NAIP.
    亚型
    IgG
    Top Product
    Discover our top product NAIP Primary Antibody
  • 应用备注
    NAIP antibody can be used for the detection of NAIP by Western blot at 0.5 to 1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    NAIP Antibody is supplied in PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,4 °C
    储存方法
    NAIP antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    NAIP (NLR Family, Apoptosis Inhibitory Protein (NAIP))
    别名
    NAIP (NAIP 产品)
    别名
    BIRC1 antibody, NLRB1 antibody, psiNAIP antibody, AV364616 antibody, Birc1a antibody, D13Lsd1 antibody, Naip antibody, Naip-rs1 antibody, NLR family apoptosis inhibitory protein antibody, NLR family, apoptosis inhibitory protein 1 antibody, NAIP antibody, Naip1 antibody
    背景
    NAIP Antibody: Neuronal apoptosis inhibitor protein (NAIP) was the first human inhibitor of apoptosis protein (IAP) identified and was discovered by its association with the neurodegenerative disorder spinal muscular atrophy. Members of the IAP family contain one to three copies of an approximately 70 amino acid motif termed baculovirus IAP repeat (BIR), these BIRs promote protein-protein interactions with various caspases such as caspase-3, -7, and -9 as well as members of the TRAF family of signal molecules. Unlike other IAPs however, NAIP requires ATP to bind caspase-9 and is not inhibited by the IAP-inhibiting molecule Smac/DIABLO, suggesting that NAIP is unique among the IAPs in its regulation of its activity. Finally, although only one human NAIP protein has been identified, other shorter NAIP mRNA transcripts have been reported.
    分子量
    Predicted: 137, 154 kDa

    Observed: 155 kDa
    基因ID
    4671
    UniProt
    Q13075
    途径
    Apoptosis, Inflammasome
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