DcR1 抗体 (Extracellular Domain)
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- 抗原 See all DcR1 (TNFRSF10C) 抗体
- DcR1 (TNFRSF10C) (Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C))
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抗原表位
- AA 90-140, Extracellular Domain
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DcR1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF)
- 纯化方法
- DcR1 Antibody is affinity chromatography purified via peptide column.
- 免疫原
- DcR1 antibody was raised against a peptide corresponding to amino acids in the extracellular domain of human DcR1 precursor. The immunogen is located within amino acids 90 - 140 of DcR1.
- 亚型
- IgG
- Top Product
- Discover our top product TNFRSF10C Primary Antibody
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anti-Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C) antibody
TNFRSF10C 适用: 人, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C) antibodyTNFRSF10C 适用: 人 FACS 宿主: 小鼠 Monoclonal TRAIL-R3-02 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C) antibody (APC)TNFRSF10C 适用: 人 FACS 宿主: 小鼠 Monoclonal TRAIL-R3-02 APC
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C) (AA 30-130) antibodyTNFRSF10C 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C) antibody (FITC)TNFRSF10C 适用: 人 FACS 宿主: 小鼠 Monoclonal TRAIL-R3-02 FITC
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C) antibodyTNFRSF10C 适用: 人 FACS, IHC 宿主: 小鼠 Monoclonal TR3-06 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C) antibody (PE)TNFRSF10C 适用: 人 FACS 宿主: 小鼠 Monoclonal TRAIL-R3-02 PE
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C) (AA 51-150) antibodyTNFRSF10C 适用: 人 WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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DcR1 antibody can be used for detection of DcR1 by Western blot at 1 μ,g/mL. An approximate 65 kDa band can be detected. Antibody can also be used for immunoflourescence starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human, mouse, and rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- DcR1 Antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,4 °C
- 储存方法
- DcR1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- 抗原
- DcR1 (TNFRSF10C) (Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C))
- 别名
- DcR1 (TNFRSF10C 产品)
- 别名
- CD263 antibody, DCR1 antibody, DCR1-TNFR antibody, LIT antibody, TRAIL-R3 antibody, TRAILR3 antibody, TRID antibody, TNFRSF10C antibody, TNF receptor superfamily member 10c antibody, TNFRSF10C antibody
- 背景
- DcR1 Antibody: Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. TRAIL/Apo2L is a new member of the TNF family and induces apoptosis of a variety of tumor cell lines. DR4 and DR5 are the recently identified functional receptors for TRAIL. Two decoy receptors for TRAIL have been identified and designated DcR1/TRID/TRAIL-R3/LIT and DcR2/TRAIL-R4/TRUNDD. DcR1 has extracellular TRAIL-binding domain but lacks intracellular signaling domain. It is a glycophospholipid-anchored cell surface protein. DcR1 transcripts are expressed in many normal human tissues but not in most cancer cell lines. Overexpression of DcR1 did not induce apoptosis, but attenuated TRAIL-induced apoptosis.
- 分子量
- 65 kDa
- 基因ID
- 8794
- UniProt
- O14798
- 途径
- Apoptosis
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