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Caspase 9 抗体 (AA 290-340)

CASP9 适用: 人, 小鼠 WB, ELISA, IF, IP, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6990323
发货至: 中国
  • 抗原 See all Caspase 9 (CASP9) 抗体
    Caspase 9 (CASP9) (Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9))
    抗原表位
    • 28
    • 16
    • 16
    • 16
    • 16
    • 9
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 290-340
    适用
    • 209
    • 130
    • 106
    • 17
    • 16
    • 16
    • 5
    人, 小鼠
    宿主
    • 205
    • 15
    克隆类型
    • 195
    • 25
    多克隆
    标记
    • 109
    • 10
    • 9
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    This Caspase 9 antibody is un-conjugated
    应用范围
    • 190
    • 76
    • 67
    • 67
    • 61
    • 48
    • 34
    • 34
    • 17
    • 16
    • 16
    • 5
    • 3
    • 3
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC)
    特异性
    Caspase-9 antibody is predicted to have no cross reactivity to other members in the caspase family.
    纯化方法
    Caspase-9 Antibody is affinity chromatography purified via peptide column.
    免疫原
    Anti-Caspase 9 antibody was raised against a peptide corresponding to 20 amino acids near the center of human Caspase 9. The immunogen is located within amino acids 290-340 of Caspase 9.
    亚型
    IgG
    Top Product
    Discover our top product CASP9 Primary Antibody
  • 应用备注
    WB: 1 μ,g/mL, ICC: 2- 5 μ,g/mL, IF: 5-20 μ,g/mL.

    Antibody validated: Western Blot in human and mouse samples, Immunocytochemistry, Immunofluorescence in human samples. All other applications and species not yet tested.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Caspase-9 Antibody is supplied in PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,4 °C
    储存方法
    Caspase-9 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    Caspase 9 (CASP9) (Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9))
    别名
    Caspase-9 (CASP9 产品)
    背景
    Caspase-9 Antibody: Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases. A novel member in the caspase family was recently identified and designated ICE-LAP6, Mch6, and Apaf-3. Caspase-9 and Apaf-1 bind to each other, which leads to caspase-9 activation. Caspase-9 is also activated by granzyme B and CPP32. Activated caspase-9 cleaves and activates caspase-3 that is one of the key proteases, being responsible for the proteolytic cleavage of many key proteins in apoptosis. Caspase-9 play a central role in cell death induced by a wide variety of apoptosis activators including TNFα, TRAIL, anti-CD-95, FADD, and TRADD. Caspase-9 is expressed in a variety of human tissues.
    分子量
    Predicted: 46kD

    Observed: 46 kD kDa
    基因ID
    842
    UniProt
    P55211
    途径
    MAPK Pathway, RTK signaling, Apoptosis, Caspase Cascade in Apoptosis, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Endopeptidase Activity
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