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IKK alpha 抗体 (C-Term)

Name: IKK alpha 抗体 (C-Term)
Brand: antibodies-online
SKU: ABIN6990273
Availability: OutOfStock

This anti-IKK alpha antibody is a 兔多克隆 antibody detecting IKK alpha in WB, ELISA, IF 和 ICC. Suitable for 人.

产品编号 ABIN6990273

发货至: 中国

Quick Overview for IKK alpha 抗体 (C-Term) (ABIN6990273)

抗原

See all IKK alpha (CHUK) 抗体

IKK alpha (CHUK) (conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK))

适用

人

宿主

兔

克隆类型

多克隆

标记

This IKK alpha antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Discover our top product CHUK Primary Antibody

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C-Term

特异性

Antibody has no cross response to IKKb or IKKg.

纯化方法

IKK alpha Antibody is affinity chromatography purified via peptide column.

免疫原

IKK alpha antibody was raised against a 19 amino acid peptide near the carboxy terminus of human IKK alpha. The immunogen is located within the last 50 amino acids of IKK alpha.

亚型

IgG
anti-conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) (C-Term) antibody
CHUK 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) (pSer176), (pSer177) antibody
CHUK 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) (AA 646-745) antibody
CHUK 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 4B8 unconjugated

anti-conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) (AA 646-745) antibody
CHUK 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 1F8 unconjugated

anti-conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) (pThr23) antibody
CHUK 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) antibody
CHUK 适用: 人 WB, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 3G12H9 unconjugated

anti-conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) (pThr23) antibody
CHUK 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) antibody
CHUK 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB2159 unconjugated

anti-conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) (N-Term) antibody
CHUK 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) (AA 551-650) antibody
CHUK 适用: 小鼠, 大鼠 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

应用备注

IKK alpha can be used for detection of IKK alpha by Western blot at 1 μ,g/mL. An 85 kDa band should be detected. Antibody can also be used for immunocytochemistry starting at 1 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

IKK alpha Antibody is supplied in PBS containing 0.02 % sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C,4 °C

储存方法

IKK alpha antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
抗原

IKK alpha (CHUK) (conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK))

别名

IKK alpha

背景

IKK alpha Antibody: Nuclear factor kappa B (NF-κ,B) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-κ,B mediates the expression of a great variety of genes in response to extracellular stimuli including IL-1, TNFa, and bacteria product LPS. NF-κ,B is associated with Iκ,B proteins in the cell cytoplasm, which inhibit NF-κ,B activity. The long-sought Iκ,B kinase (IKK), which phosphorylates Iκ,B, and mediates Iκ,B degradation and NF-κ,B activation, was recently identified by several laboratories. IKK is a serine protein kinase, and the IKK complex contains alpha and beta subunits (IKKα, and IKKβ,). IKKα, and IKKβ, interact with each other and both are essential for the NF-κ,B activation. IKKα, specifically phosphorylates IkB-alpha. IKKα, is expressed in variety of human tissues.

分子量

85 kDa

基因ID

1147

UniProt

O15111

途径

PI3K-Akt Signaling, NF-kappaB Signaling, RTK signaling, TCR Signaling, TLR signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins