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STAT1 抗体 (C-Term)

STAT1 适用: 人, 小鼠, 大鼠 WB, ELISA, IP, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6990235
发货至: 中国
  • 抗原 See all STAT1 抗体
    STAT1 (Signal Transducer and Activator of Transcription 1, 91kDa (STAT1))
    抗原表位
    • 45
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    C-Term
    适用
    • 171
    • 99
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    • 7
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    人, 小鼠, 大鼠
    宿主
    • 172
    • 17
    • 2
    克隆类型
    • 162
    • 29
    多克隆
    标记
    • 106
    • 11
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    • 5
    • 5
    • 5
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    • 3
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    This STAT1 antibody is un-conjugated
    应用范围
    • 132
    • 63
    • 50
    • 42
    • 36
    • 26
    • 26
    • 19
    • 19
    • 6
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    Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    At least two isoforms of STAT1 are known to exist, this antibody will only recognize the larger isoform.
    纯化方法
    STAT1 alpha Antibody is Antibody is DEAE purified.
    免疫原
    Anti-STAT1 alpha antibody was raised against a peptide corresponding to 38 amino acids near the carboxy terminus of human STAT1 alpha. The immunogen is located within the last 50 amino acids of STAT1 alpha.
    亚型
    IgG
    Top Product
    Discover our top product STAT1 Primary Antibody
  • 应用备注
    WB: 0.5-1 μ,g/mL, IF: 20 μ,g/mL, IHC: 2.5 μ,g/mL, ICC: 10 μ,g/mL .

    Antibody validated: Western Blot in human, mouse and rat samples, Immunofluorescence, Immunohistochemistry and Immunocytochemistry in human samples. All other applications and species not yet tested.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    STAT1 alpha Antibody is supplied in PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,4 °C
    储存方法
    STAT1 alpha antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    STAT1 (Signal Transducer and Activator of Transcription 1, 91kDa (STAT1))
    别名
    STAT1 alpha (STAT1 产品)
    别名
    CANDF7 antibody, ISGF-3 antibody, STAT91 antibody, 2010005J02Rik antibody, AA408197 antibody, XStat1 antibody, STAT4 antibody, DD6G4-4 antibody, STAT antibody, STAT1 antibody, dZ182H3.3 antibody, si:by134g18.2 antibody, si:by51f19.1 antibody, si:dz182h3.3 antibody, si:dz199m19.1 antibody, si:dz73o4.2 antibody, stat1 antibody, signal transducer and activator of transcription 1 antibody, signal transducer and activator of transcription 1 L homeolog antibody, signal transducer and activator of transcription 1, 91kDa antibody, signal transducer and activator of transcription 4 antibody, signal transducer and activator of transcription 1a antibody, STAT1 antibody, Stat1 antibody, stat1.L antibody, stat4 antibody, stat1a antibody
    背景
    STAT1 alpha Antibody: STATs (signal transducers and activators of transcription) are a family of cytoplasmic latent transcription factors that are activated to regulate gene expression in response to a large number of extracellular signaling polypeptides including cytokines, interferons, and growth factors. After phosphorylation by JAK tyrosine kinases, STATs enter the nucleus to regulate transcription of many different genes. Among the seven STATs (Stat1, Stat2, Stat3, Stat4, Stat5a, Stat5b, and Stat6), Stat1, Stat3, Stat5a, and Stat5b have a wide activation profile. STAT1 is activated by many different ligands including IFN family (IFN-α, IFN-β, IFN-γ, and IL-10), gp130 family (IL-6, IL-11, LIF, CNTF, and G-CSF), and receptor tyrosine kinases (EGF, PDGF, and CSF-1).
    分子量
    Predicted: 87kD

    Observed: 87 kD kDa
    基因ID
    6772
    NCBI登录号
    NP_009330
    UniProt
    P42224
    途径
    JAK/STAT Signaling, RTK signaling, Interferon-gamma Pathway, Response to Growth Hormone Stimulus, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Hepatitis C, CXCR4-mediated Signaling Events
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