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IKKi/IKKe 抗体 (C-Term)

IKBKE 适用: 人, 小鼠 WB, ELISA, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6990163
发货至: 中国
  • 抗原 See all IKKi/IKKe (IKBKE) 抗体
    IKKi/IKKe (IKBKE) (Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase epsilon (IKBKE))
    抗原表位
    • 15
    • 9
    • 8
    • 8
    • 7
    • 6
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 60
    • 25
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 70
    • 6
    克隆类型
    • 61
    • 15
    多克隆
    标记
    • 33
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    This IKKi/IKKe antibody is un-conjugated
    应用范围
    • 60
    • 32
    • 17
    • 16
    • 16
    • 12
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    特异性
    It has no cross response to IKKa, IKKb, or IKKy.
    纯化方法
    IKK epsilon Antibody is affinity chromatography purified via peptide column.
    免疫原
    Anti-IKK epsilon antibody was raised against a peptide corresponding to 16 amino acids near the carboxy terminus of human IKK epsilon. The immunogen is located within the last 50 amino acids of IKK epsilon.
    亚型
    IgG
    Top Product
    Discover our top product IKBKE Primary Antibody
  • 应用备注
    WB: 1-2 μ,g/mL, IHC: 10 μ,g/mL, IF: 20 μ,g/mL.

    Antibody validated: Western Blot in human and mouse samples, Immunohistochemistry in human samples, Immunofluorescence in human samples. All other applications and species not yet tested.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    IKK epsilon Antibody is supplied in PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,4 °C
    储存方法
    IKK epsilon antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    IKKi/IKKe (IKBKE) (Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase epsilon (IKBKE))
    别名
    IKK epsilon (IKBKE 产品)
    别名
    zgc:100844 antibody, IKBKE antibody, MGC130907 antibody, IKK-E antibody, IKK-i antibody, IKKE antibody, IKKI antibody, AW558201 antibody, IKKepsilon antibody, Ikki antibody, inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon antibody, inhibitor of nuclear factor kappa B kinase subunit epsilon antibody, inhibitor of nuclear factor kappa B kinase subunit epsilon L homeolog antibody, inhibitor of kappaB kinase epsilon antibody, IKBKE antibody, ikbke antibody, ikbke.L antibody, Ikbke antibody
    背景
    IKK epsilon Antibody: Nuclear factor kappa B (NF-κ,B) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-κ,B mediates the expression of a great variety of genes in response to extracellular stimuli. NF-κ,B is associated with Iκ,B proteins in the cell cytoplasm, which inhibit NF-κ,B activity. Iκ,B is phosphorylated by Iκ,B kinase (IKK) complex that contains IKKα, IKKβ, and IKKγ,. A novel molecule in the IKK complex was recently identified and designated IKKε,/IKK-i. IKK epsilon is required for the activation of NF-κ,B by PMA and T cell receptors but not by TNFα, and IL-1. IKKε,/IKK-i message is expressed in a variety of tissues and is inducible by TNFα, IL-1, and LPS.
    分子量
    Predicted: 80kD

    Observed: 80 kD kDa
    基因ID
    9641
    UniProt
    Q14164
    途径
    TLR signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades
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