Caspase 9 抗体 (AA 231-330) (HRP)
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- 抗原 See all Caspase 9 (CASP9) 抗体
- Caspase 9 (CASP9) (Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9))
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抗原表位
- AA 231-330
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Caspase 9 antibody is conjugated to HRP
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人, 小鼠, 大鼠
- 预测反应
- Cow,Sheep,Pig,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human Caspase-9
- 亚型
- IgG
- Top Product
- Discover our top product CASP9 Primary Antibody
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anti-Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9) (AA 1-98) antibody
CASP9 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9) (AA 11-120) antibodyCASP9 适用: 人, 小鼠, 大鼠, 小鸡, 犬, 兔 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9) (AA 1-200) antibodyCASP9 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9) (AA 1-200) antibodyCASP9 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9) (AA 1-416) antibodyCASP9 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 3B8-4G2 unconjugated
anti-Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9) (AA 271-314) antibodyCASP9 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9) (AA 331-416) antibodyCASP9 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9) (pThr125) antibodyCASP9 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9) (Cleaved-Asp353) antibodyCASP9 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9) antibodyCASP9 适用: 人 WB, IP, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- Caspase 9 (CASP9) (Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9))
- 别名
- Caspase-9 (CASP9 产品)
- 背景
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Synonyms: Caspase-9 subunit p35, Apaf-3, APAF 3, APAF3, Apoptosis related cysteine peptidase, Apoptotic protease activating factor 3, Apoptotic protease MCH 6, Apoptotic protease MCH6, CASP 9, CASP9, Caspase 9, Caspase 9 apoptosis related cysteine protease, Caspase 9 precursor, Caspase 9c, Caspase9, Caspase9 subunit p10, ICE LAP6, ICE like apoptotic protease 6, RNCASP9, MCH 6, MCH6, OTTHUMP00000044594, CASP9_HUMAN.
Background: Caspase 9 (also known as ICE like apoptotic protease 6 (ICE LAP6), apoptotic protease Mch6, and apoptotic protease activating factor 3 (Apaf3)) is a member of the peptidase family C14 that contains a CARD domain. This caspase is active as a heterotetramer and has been reported to have two isoforms. ProCaspase 9 has been reported to be approximately 47 kD. This caspase is present in the cytosol and, upon activation, translocates to the mitochondria. Caspase 9 is involved in the caspase activation cascade responsible for apoptosis execution and cleaves/activates Caspase 3 and Caspase 6. Caspase 9 is inhibited by the dominant negative isoform, BclXL, cIAP1, cIAP2, XIAP, and Livin. This caspase becomes activated when recruited to Apaf1/cytochrome c complex, and following cleavage by Apaf1, granzyme B, Caspase 3, possibly Caspase 8 and Caspase 10 into large p37 and small p10 subunits. Caspase 9 intereacts with BIRC7 and has been shown to cleave PARP and vimentin.?
- 基因ID
- 842
- UniProt
- P55211
- 途径
- MAPK Pathway, RTK signaling, Apoptosis, Caspase Cascade in Apoptosis, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Endopeptidase Activity
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