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Histone 3 抗体 (acLys9)

H3 适用: 人, 小鼠 WB, IF, ChIP, DB, ICC, ChIP-seq 宿主: 小鼠 Monoclonal 1B10 unconjugated
产品编号 ABIN6972004
发货至: 中国
  • 抗原 See all Histone 3 (H3) 抗体
    Histone 3 (H3)
    抗原表位
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    acLys9
    适用
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    人, 小鼠
    宿主
    • 1218
    • 242
    • 8
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    小鼠
    克隆类型
    • 1121
    • 350
    • 1
    单克隆
    标记
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    This Histone 3 antibody is un-conjugated
    应用范围
    • 1058
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    Western Blotting (WB), Immunofluorescence (IF), Chromatin Immunoprecipitation (ChIP), Dot Blot (DB), Immunocytochemistry (ICC), ChIP DNA-Sequencing (ChIP-seq)
    产品特性
    Histone H3 is one of the core components of the nucleosome, the basic building block of chromatin. Histones are subject to a variety of chemical modifications, including post-translational modifications of the histone proteins and the methylation of cytosine residues in the DNA. Reported histone modifications include acetylation, methylation, phosphorylation, ubiquitylation, glycosylation, ADP-ribosylation, carbonylation and SUMOylation, these modifications play a major role in regulating gene expression. Acetylation of Lys9 is associated with trascriptional activation of genes. Histone H3K9ac antibody (mAb) (Clone 1B10) was raised in a Mouse host. It has been validated for use in Chromatin Immunoprecipitation, ChIP-Seq, Dot blot, Immunocytochemistry, Immunofluorescence and Western blot, it has been shown to react with Human and Mouse samples, but it is predicted that it will react with a wide range of sample types.
    纯化方法
    Protein A Chromatography
    免疫原
    The Histone H3 acetyl Lys9 antibody was raised against a peptide including acetyl-lysine 9 of human Histone H3.
    克隆位点
    1B10
    亚型
    IgG3
    Top Product
    Discover our top product H3 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    Purified IgG in 0.1 M Tris, pH 8.0, 1 M NaCl with 30 % glycerol and 0.035 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
  • Kee, Thudium, Renner, Glastad, Palozola, Zhang, Li, Lan, Cesare, Poleshko, Kiseleva, Truitt, Cardenas-Diaz, Zhang, Xie, Kotton, Alysandratos, Epstein, Shi et al.: "SARS-CoV-2 disrupts host epigenetic regulation via histone mimicry." in: Nature, (2022) (PubMed).

  • 抗原
    Histone 3 (H3)
    别名
    Histone H3 (H3 产品)
    别名
    H-3 antibody, histocompatibility 3 antibody, H3 antibody
    分子量
    17
    NCBI登录号
    NP_003522
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