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- 抗原 See all RUNX1T1 抗体
- RUNX1T1 (Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1))
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抗原表位
- Internal Region
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RUNX1T1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP)
- 产品特性
- ETO / RUNX1T1 (AML1T1, CBFA2T1, MTG8, ZMYND2) belongs to a family of evolutionarily conserved nuclear factors that act as a transcriptional corepressor. ETO / RUNX1T1 does not interact directly with DNA but is recruited by transcription factors such as PLZF, BCL6, TAL1/SCL, Gfi1and Heb recruit nuclear co-repressors such as NCoR, SIN3, and SMRT / NCoR2, which in turn interact with histone deacetylase (HDAC) to mediate transcriptional repression. ETO / RUNX1T1 contains four evolutionarily conserved functional domains called nervy homology regions (NHRs) involved in protein-protein interaction. ETO / RUNX1T1 is frequently found as a fusion partner of AML1 in acute myeloid leukemia with the t(8,21) translocation which gives rise to the AML-ETO fusion protein. ETO / RUNX1T1 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Immunoprecipitation and Western blot, it has been shown to react with Human samples.
- 纯化方法
- Affinity Purified
- 免疫原
- This ETO / RUNX1T1 antibody was raised against a peptide within the internal region of human ETO / RUNX1T1.
- 亚型
- IgG
- Top Product
- Discover our top product RUNX1T1 Primary Antibody
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anti-Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1) (AA 416-525) antibody
RUNX1T1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 5A12 unconjugated
anti-Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1) (N-Term) antibodyRUNX1T1 适用: 人 ELISA, ChIP, ChIP-seq 宿主: 兔 Polyclonal unconjugated
anti-Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1) (AA 416-525) antibodyRUNX1T1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1) (AA 1-577) antibodyRUNX1T1 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1) (AA 335-510) antibodyRUNX1T1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1) antibodyRUNX1T1 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1) (AA 221-270) antibodyRUNX1T1 适用: 人, 小鼠, 大鼠, 犬, 斑马鱼, 兔, 豚鼠, 马, Pig, 小鸡, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1) (AA 288-337) antibodyRUNX1T1 适用: 人, 大鼠, 犬, 兔, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1) (N-Term) antibodyRUNX1T1 适用: 人, 小鼠, 大鼠, 犬, 斑马鱼, 兔, 豚鼠, 马, Cow, Pig, 小鸡, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1) antibodyRUNX1T1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 缓冲液
- Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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- 抗原
- RUNX1T1 (Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1))
- 别名
- ETO / RUNX1T1 (RUNX1T1 产品)
- 别名
- MTG8 antibody, si:ch211-232j17.1 antibody, wu:fi14b07 antibody, zgc:154044 antibody, AML1T1 antibody, CBFA2T1 antibody, CDR antibody, ETO antibody, ZMYND2 antibody, Cbfa2t1h antibody, Cbfa2t1 antibody, runt-related transcription factor 1; translocated to, 1 (cyclin D-related) antibody, RUNX1 translocation partner 1 L homeolog antibody, RUNX1 translocation partner 1 antibody, runx1t1 antibody, runx1t1.L antibody, RUNX1T1 antibody, Runx1t1 antibody
- 分子量
- 68 kDa
- NCBI登录号
- NP_783553
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