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IL-6 抗体 (Biotin)

This anti-IL-6 antibody is a 大鼠 单克隆 antibody detecting IL-6 in ELISA 和 ELISpot. Suitable for 人 和 Non-Human Primate. This Primary Antibody has been cited in 4+ publications.
产品编号 ABIN6963872
发货至: 中国

Quick Overview for IL-6 抗体 (Biotin) (ABIN6963872)

抗原

See all IL-6 (IL6) 抗体
IL-6 (IL6) (Interleukin 6 (IL6))

适用

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人, Non-Human Primate

宿主

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大鼠

克隆类型

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单克隆

标记

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This IL-6 antibody is conjugated to Biotin

应用范围

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ELISA, ELISpot

克隆位点

39C3
  • 特异性

    Native and recombinant IL-6

    交叉反应 (详细)

    The monoclonal antibody cross-reacts with IL-6 from non-human primates.

    产品特性

    This monoclonal antibody enables specific detection of human IL-6 in immunoassays such as ELISpot, FluoroSpot, and ELISA. Serum/Plasma samples

    纯化方法

    Biotinylated through reaction with a N-hydroxysuccinimide ester of biotin.,Purified from in vitro cultures by protein G affinity chromatography.

    过滤

    0.2 μm filtered

    免疫原

    Recombinant human IL-6

    亚型

    IgG2a
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    ABIN6963872 and ABIN7448315 is recommended as detection mAb in ELISpot, FluoroSpot, and ELISA in combination with capture mAb ABIN6963871, ABIN7448314 and ABIN6964024 .

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    supplied at 1 mg/mL in PBS with 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.

    有效期

    18 months
  • Järver, Dondalska, Poux, Sandberg, Bergenstråhle, Sköld, Dereuddre-Bosquet, Martinon, Pålsson, Zaghloul, Brodin, Sander, Lennox, Behlke, El-Andaloussi, Lehtiö, Lundeberg, LeGrand, Spetz: "Single-Stranded Nucleic Acids Regulate TLR3/4/7 Activation through Interference with Clathrin-Mediated Endocytosis." in: Scientific reports, Vol. 8, Issue 1, pp. 15841, (2019) (PubMed).

    Zhenjiang, Rao, Luo, Valentini, von Landenberg, Meng, Sinclair, Hoffmann, Karbach, Altmannsberger, Jäger, Peredo, Dodoo, Maeurer: "Cytokine Networks and Survivin Peptide-Specific Cellular Immune Responses Predict Improved Survival in Patients With Glioblastoma Multiforme." in: EBioMedicine, Vol. 33, pp. 49-56, (2018) (PubMed).

    Phuah, Wong, Gideon, Maiello, Coleman, Hendricks, Ruden, Cirrincione, Chan, Lin, Flynn: "Effects of B Cell Depletion on Early Mycobacterium tuberculosis Infection in Cynomolgus Macaques." in: Infection and immunity, Vol. 84, Issue 5, pp. 1301-1311, (2017) (PubMed).

    Min, Wang, Yuan, Kuang, Zhao: "Effects of repeated tuberculin skin testings on immune responses in experimental monkeys." in: Journal of animal science and technology, Vol. 56, pp. 32, (2015) (PubMed).

  • 抗原

    IL-6 (IL6) (Interleukin 6 (IL6))

    别名

    IL6

    基因ID

    3569

    途径

    TLR signaling, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagy, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome
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