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IL-1 beta 抗体

This anti-IL-1 beta antibody is a 小鼠 单克隆 antibody detecting IL-1 beta in ELISA 和 ELISpot. Suitable for 人. This Primary Antibody has been cited in 4+ publications.
产品编号 ABIN6963831
发货至: 中国

Quick Overview for IL-1 beta 抗体 (ABIN6963831)

抗原

See all IL-1 beta (IL1B) 抗体
IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This IL-1 beta antibody is un-conjugated

应用范围

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ELISA, ELISpot

克隆位点

MT175
  • 特异性

    Native and recombinant human IL-1β. The antibody binds to the pro-form and active form of IL-1β. No cross-reactivity with IL-1α.

    交叉反应 (详细)

    This monoclonal antibody enables sensitive and specific detection of human IL-1β in immunoassays such as ELISA and ELISpot. The antibody binds to the pro-form and the active form of IL-1β. It does not cross-react with IL-1α.

    纯化方法

    Purified from in vitro cultures by protein G affinity chromatography.

    过滤

    0.2 μm filtered

    免疫原

    Recombinant human IL-1beta

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    supplied at 0.5 mg/mL in PBS with 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.

    有效期

    18 months
  • Lang, Lee, Elgass, Pinar, Tate, Aitken, Fan, Creed, Deen, Traore, Mueller, Stanisic, Baiwog, Skene, Wilce, Mansell, Morand, Harris: "Macrophage migration inhibitory factor is required for NLRP3 inflammasome activation." in: Nature communications, Vol. 9, Issue 1, pp. 2223, (2018) (PubMed).

    Chen, Messina, Germano, Bonnici, Freyne, Cheung, Goldsmith, Kollmann, Levin, Burgner, Curtis: "Innate immune responses following Kawasaki disease and toxic shock syndrome." in: PLoS ONE, Vol. 13, Issue 2, pp. e0191830, (2018) (PubMed).

    Palizgir, Akhtari, Mahmoudi, Mostafaei, Rezaiemanesh, Shahram: "Curcumin reduces the expression of interleukin 1β and the production of interleukin 6 and tumor necrosis factor alpha by M1 macrophages from patients with Behcet's disease." in: Immunopharmacology and immunotoxicology, Vol. 40, Issue 4, pp. 297-302, (2018) (PubMed).

    Gille-Johnson, Smedman, Gudmundsdotter, Somell, Nihlmark, Paulie, Andersson, Gårdlund: "Circulating monocytes are not the major source of plasma cytokines in patients with sepsis." in: Shock (Augusta, Ga.), Vol. 38, Issue 6, pp. 577-83, (2013) (PubMed).

  • 抗原

    IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))

    别名

    IL1B

    基因ID

    3553

    途径

    NF-kappaB Signaling, Interferon-gamma Pathway, TLR signaling, Negative Regulation of Hormone Secretion, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Autophagy, Cancer Immune Checkpoints, Inflammasome
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