CD11c 抗体
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- 抗原 See all CD11c (ITGAX) 抗体
- CD11c (ITGAX) (Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD11c antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Immunofluorescence (IF), Immunoprecipitation (IP)
- 交叉反应
- Baboon, Chimpanzee, Cynomolgus, 猕猴
- 纯化方法
- This monoclonal antibody preparation was purified from tissue culture supernatant via affinity chromatography. For In Vivo Ready™ (IVR) products, each preparation is also evaluated for endotoxin levels using the LAL assay. It is recommended to store the product undiluted at 4°C. Do not freeze.
- 克隆位点
- 3-9
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product ITGAX Primary Antibody
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anti-Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX) antibody
ITGAX 适用: 人, 小鼠, 大鼠 IHC, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX) antibody (FITC)ITGAX 适用: 人, 猴 FACS 宿主: 小鼠 Monoclonal BU15 FITC
anti-Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX) (AA 1119-1145) antibodyITGAX 适用: 人 FACS, IHC, WB, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX) (AA 100-350) antibodyITGAX 适用: 人 IHC, WB, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX) antibodyITGAX 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX) antibodyITGAX 适用: 人, 猴 FACS, IP, IHC (fro) 宿主: 小鼠 Monoclonal BU15 unconjugated
anti-Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX) (AA 102-279) antibodyITGAX 适用: 人 FACS, IHC, WB, ELISA, ICC, Neut 宿主: 小鼠 Monoclonal 6G2D1 unconjugated
anti-Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX) (AA 1119-1145), (C-Term) antibodyITGAX 适用: 人 FACS, WB, IF, IHC (p) 宿主: 兔 Polyclonal RB21771 unconjugated
anti-Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX) (AA 637-827) antibodyITGAX 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal ITGAX-1242 unconjugated
anti-Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX) (N-Term) antibodyITGAX 适用: 人, 小鼠 IHC, WB, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- This purified format is guaranteed to be >90 % pure as determined by SDS-PAGE analysis.
- 说明
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0.5 mg/mL
- 限制
- 仅限研究用
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- 缓冲液
- 10 mM NaH2PO4, 150 mM NaCl, 0.09 % Sodium azide, pH 7.2
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- 2-8°C
- 有效期
- 12 months
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- 抗原
- CD11c (ITGAX) (Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX))
- 别名
- CD11c (ITGAX 产品)
- 别名
- CD11C antibody, SLEB6 antibody, RGD1561123 antibody, AI449405 antibody, Cd11c antibody, Cr4 antibody, N418 antibody, integrin subunit alpha X antibody, integrin alpha X antibody, ITGAX antibody, Itgax antibody
- 背景
- The 3.9 antibody reacts with human CD11c, also known as integrin alpha X. This 150 kDa cell surface glycoprotein is part of a family of integrin receptors that mediate adhesion between cells (cell-cell) and components of the extracellular matrix, e.g. fibrinogen (cell-matrix). In addition, integrins are active signaling receptors which recruit leukocytes to inflammatory sites and promote cell activation. Complete, functional integrin receptors consist of distinct combinations of integrin chains which are differentially expressed. Integrin alpha X (CD11c) assembles with Integrin beta-2 (CD18) into a receptor known as CR4 which can bind and induce signaling through ICAMs and VCAM-1 on endothelial cells and can also facilitate removal of iC3b bearing foreign cells.The 3.9 antibody is widely used as a marker for CD11c expression on dendritic cells (DC), often in parallel with markers for CD11b, for identification of developmental stages and mature subsets of this cell type. CD11c is prominently expressed on tissue macrophages, and is also detected on activated neutrophils, granulocytes, some types of activated T cells and intestinal intraepithelial lymphocytes (IEL). The antibody is reported to be cross-reactive with Baboon, Chimpanzee, Cynomolgus and Rhesus CD11c.
- 基因ID
- 3687
- UniProt
- P20702
- 途径
- Complement System, Activated T Cell Proliferation, Integrin Complex
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