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PD-1 抗体 (APC)

PDCD1 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal RMP1-30 APC
产品编号 ABIN6961282
发货至: 中国
  • 抗原 See all PD-1 (PDCD1) 抗体
    PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
    适用
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    小鼠
    宿主
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    大鼠
    克隆类型
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    单克隆
    标记
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    This PD-1 antibody is conjugated to APC
    应用范围
    • 114
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    Flow Cytometry (FACS)
    纯化方法
    This monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation. It is recommended to store the product undiluted at 4°C, and protected from prolonged exposure to light. Do not freeze.
    克隆位点
    RMP1-30
    亚型
    IgG2b kappa
    Top Product
    Discover our top product PDCD1 Primary Antibody
  • 应用备注
    This antibody preparation has been quality-tested for flow cytometry using mouse spleen cells, or an appropriate cell type (where indicated). Please refer to the figure legend for the optimal concentration used to stain the tissue shown. We recommend titrating the antibody under your specific conditions to determine the optimal concentration of antibody needed in your experimental system.
    说明

    0.2 mg/mL

    限制
    仅限研究用
  • 缓冲液
    10 mM NaH2PO4, 150 mM NaCl, 0.09 % Sodium azide, 0.1 % gelatin, pH 7.2
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    2-8°C protected from light
    有效期
    12 months
  • 抗原
    PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
    别名
    CD279 (PD-1) (PDCD1 产品)
    别名
    CD279 antibody, PD-1 antibody, PD1 antibody, SLEB2 antibody, hPD-1 antibody, hPD-l antibody, Ly101 antibody, Pdc1 antibody, programmed cell death 1 antibody, PDCD1 antibody, Pdcd1 antibody
    背景
    The RMP1-30 antibody is specific for mouse CD279, also known as programmed death-1 (PD-1), a 55 kDa glycoprotein member of the Ig superfamily of molecules. PD-1 exists in a monomeric form that is expressed by CD4- CD8- thymocytes, where it participates in the processes of clonal selection, elimination of autoreactive lymphocytes, and development of tolerance. PD-1 expression is also inducible upon activation of mature T cells, where it has been proposed to interact with the co-stimulatory receptor CD80 to limit T cell activation. Two ligands for PD-1, known as PD-L1 (B7-H1) and PD-L2 (B7-DC) are differentially expressed on T and B cells, monocytes, macrophages, NK cells or dendritic cells.
    基因ID
    18566
    UniProt
    Q02242
    途径
    Cancer Immune Checkpoints
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