Immunofluorescence (IF), ELISA, Dot Blot (DB), ChIP DNA-Sequencing (ChIP-seq)
交叉反应
人, 小鼠
纯化方法
Affinity purified polyclonal antibody in PBS containing 0.05% azide and 0.05% ProClin 300.
免疫原
Polyclonal antibody raised in rabbit against the region of histone H4 containing the acetylated lysines 5, 8, 12 and 16 (H4K5,8,12,16ac), using a KLH-conjugated synthetic peptide
Optional[synonyms]: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.