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Histone H4 产品

(Histone H4)

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Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails\; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated\; this record represents the centromeric copy. [provided by RefSeq, Jul 2008].

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Featured Histone H4 Categories

Histone H4 抗体

High quality antibodies with extensive validation data.

Histone H4 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

Histone H4 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Histone H4 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, IF
Validations
  • (6)
Cat. No. ABIN7263243
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC, IF
Validations
  • (6)
Cat. No. ABIN7257734
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF, IP, ChIP, ChIP-seq
Validations
  • (6)
Cat. No. ABIN7267747
Quantity 100 μL
Datasheet Datasheet

Recommended Histone H4 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (4)
  • (5)
Cat. No. ABIN6574152
Quantity 96 tests
Datasheet Datasheet
Reactivity Dog
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6956584
Quantity 96 tests
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1381206
Quantity 96 tests
Datasheet Datasheet

Recommended Histone H4 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7406626
Quantity 100 μg
Datasheet Datasheet
Reactivity Cat, Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rat, Rhesus Monkey
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7414570
Quantity 100 μg
Datasheet Datasheet
Reactivity Xenopus laevis
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN2669514
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our Histone H4 Products

Sun, Zhao, Mu, Zhang, Cui, Wu, Alam, Wang, Ma: "Dexmedetomidine inhibits astrocyte pyroptosis and subsequently protects the brain in in vitro and in vivo models of sepsis." in: Cell death & disease, Vol. 10, Issue 3, pp. 167, (2020) (PubMed).

Stixová, Komůrková, Svobodová Kovaříková, Bártová: "UVA irradiation strengthened an interaction between UBF1/2 proteins and H4K20 di-/tri-methylation." in: Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology, Vol. 27, Issue 1-2, pp. 41-55, (2019) (PubMed).

Clouaire, Rocher, Lashgari, Arnould, Aguirrebengoa, Biernacka, Skrzypczak, Aymard, Fongang, Dojer, Iacovoni, Rowicka, Ginalski, Côté, Legube: "Comprehensive Mapping of Histone Modifications at DNA Double-Strand Breaks Deciphers Repair Pathway Chromatin Signatures." in: Molecular cell, Vol. 72, Issue 2, pp. 250-262.e6, (2018) (PubMed).

Moiseeva, Hood, Schamus, OConnor, Conrads, Bakkenist: "ATR kinase inhibition induces unscheduled origin firing through a Cdc7-dependent association between GINS and And-1." in: Nature communications, Vol. 8, Issue 1, pp. 1392, (2018) (PubMed).

Bulusu, Tumanov, Michalopoulou, van den Broek, MacKay, Nixon, Dhayade, Schug, Vande Voorde, Blyth, Gottlieb, Vazquez, Kamphorst: "Acetate Recapturing by Nuclear Acetyl-CoA Synthetase 2 Prevents Loss of Histone Acetylation during Oxygen and Serum Limitation." in: Cell reports, Vol. 18, Issue 3, pp. 647-658, (2017) (PubMed).

Young, Hillyer, Hokamp, Fitzpatrick, Konstantinov, Welty, Ness, Werner-Washburne, Fleming, Osley: "Distinct histone methylation and transcription profiles are established during the development of cellular quiescence in yeast." in: BMC genomics, Vol. 18, Issue 1, pp. 107, (2017) (PubMed).

Gonzalez-Vasconcellos, Schneider, Anastasov, Alonso-Rodriguez, Sanli-Bonazzi, Fernández, Atkinson: "The Rb1 tumour suppressor gene modifies telomeric chromatin architecture by regulating TERRA expression." in: Scientific reports, Vol. 7, pp. 42056, (2017) (PubMed).

Meisenberg, Ashour, El-Shafie, Liao, Hodgson, Pilborough, Khurram, Downs, Ward, El-Khamisy: "Epigenetic changes in histone acetylation underpin resistance to the topoisomerase I inhibitor irinotecan." in: Nucleic acids research, Vol. 45, Issue 3, pp. 1159-1176, (2017) (PubMed).

Dal-Pra, Hodgkinson, Mirotsou, Kirste, Dzau: "Demethylation of H3K27 Is Essential for the Induction of Direct Cardiac Reprogramming by miR Combo." in: Circulation research, Vol. 120, Issue 9, pp. 1403-1413, (2017) (PubMed).

Meers, Henriques, Lavender, McKay, Strahl, Duronio, Adelman, Matera: "Histone gene replacement reveals a post-transcriptional role for H3K36 in maintaining metazoan transcriptome fidelity." in: eLife, Vol. 6, (2017) (PubMed).

Synonyms and alternative names related to Histone H4

histone cluster 1, H4a L homeolog (hist1h4a.L), histone cluster 1 H4 family member B (Hist1h4b), histone cluster 2, H4 (Hist2h4), histone cluster 2 H4 family member a (HIST2H4A), histone H4 (H4), histone H4 (H4C14), histone H4 (HIS4), histone H4 (HIST2H4), Histone H4 replacement (His4r), Histone H4 (his-38), BcDNA:RH52884, CG3379, Dmel\CG3379, F8N16.2, F8N16_2, FO108, H1ft, H4, H4/n, H4C7, H4C13, H4F2, H4FN, H4r, His4-88CD, His4R, hist1h4l, HIST2H4, Hist4, Hist4h4, histone H4, X04652

Protein level used designations for Histone H4

  • histone 1, H4l
  • histone H4
  • germinal histone H4
  • histone 2, H4
  • H4 histone family, member N
  • H4 histone, family 2
  • histone 2, H4a
  • histone IV, family 2
  • H4.1
  • GRMZM2G084195
  • GRMZM2G149178
  • GRMZM2G181153
  • hypothetical protein
  • CG3379-PA
  • CG3379-PB
  • CG3379-PC
  • CG3379-PD
  • His4r-PA
  • His4r-PB
  • His4r-PC
  • His4r-PD
  • histone H4 replacement
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