Histone H2A 产品
(Histone H2A)
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Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Acts as a Polycomb group (PcG) protein required to maintain the transcriptionally repressive state of homeotic genes of the animal throughout development. Required for histone H3 'Lys-9' methylation and histone H4 'Lys-12' acetylation, two modifications that are essential for heterochromatin formation. Also involved in DNA double strand break (DSB) repair. Essential for early development.
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Featured Histone H2A Categories
Histone H2A 抗体
High quality antibodies with extensive validation data.
Histone H2A ELISA试剂盒
Reliable ELISA kits for a wide range of species.
Histone H2A 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Histone H2A 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (7)
Cat. No.
ABIN7267725
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (5)
Cat. No.
ABIN6136140
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
IHC, IF
Validations
- (4)
Cat. No.
ABIN7258522
Quantity
200 μL
Datasheet
Datasheet
Recommended Histone H2A ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6956582
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Competition ELISA
Validations
Cat. No.
ABIN2112539
Quantity
96 tests
Datasheet
Datasheet
Recommended Histone H2A 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7123346
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN3126014
Quantity
1 mg
Datasheet
Datasheet
Reactivity
CHO cells
Source
Insect Cells
Validations
Cat. No.
ABIN7126067
Quantity
0.5 mg
Datasheet
Datasheet
Latest Publications for our Histone H2A Products
: "Molecular Signature and Mechanisms of Hepatitis D Virus-Associated Hepatocellular Carcinoma." in: Molecular cancer research : MCR, Vol. 16, Issue 9, pp. 1406-1419, (2018) (PubMed).: "Distinct histone methylation and transcription profiles are established during the development of cellular quiescence in yeast." in: BMC genomics, Vol. 18, Issue 1, pp. 107, (2017) (PubMed).
: "RNA m6A methylation regulates the ultraviolet-induced DNA damage response." in: Nature, Vol. 543, Issue 7646, pp. 573-576, (2017) (PubMed).
: "The transcription factor GATA3 is required for homologous recombination repair by regulating CtIP expression." in: Oncogene, Vol. 36, Issue 36, pp. 5168-5176, (2017) (PubMed).
: "PP2A Controls Genome Integrity by Integrating Nutrient-Sensing and Metabolic Pathways with the DNA Damage Response." in: Molecular cell, Vol. 67, Issue 2, pp. 266-281.e4, (2017) (PubMed).
: "Probing the catalytic functions of Bub1 kinase using the small molecule inhibitors BAY-320 and BAY-524." in: eLife, Vol. 5, (2017) (PubMed).
: "Borealin dimerization mediates optimal CPC checkpoint function by enhancing localization to centromeres and kinetochores." in: Nature communications, Vol. 6, pp. 6775, (2015) (PubMed).
: "Snf2h-mediated chromatin organization and histone H1 dynamics govern cerebellar morphogenesis and neural maturation. ..." in: Nature communications, Vol. 5, pp. 4181, (2014) (PubMed).
: "An RNA polymerase II-coupled function for histone H3K36 methylation in checkpoint activation and DSB repair." in: Nature communications, Vol. 5, pp. 3965, (2014) (PubMed).
: "The yeast Cyc8-Tup1 complex cooperates with Hda1p and Rpd3p histone deacetylases to robustly repress transcription of the subtelomeric FLO1 gene." in: Biochimica et biophysica acta, Vol. 1839, Issue 11, pp. 1242-55, (2014) (PubMed).
Synonyms and alternative names related to Histone H2A
Histone H2A variant (His2Av), putative histone H2A (LMJF_17_0280), histone H2A (H2AX), histone cluster 1 H2A family member F (Hist1h2af), histone H2A-like (LOC100425378), histone cluster 1, H2af (Hist1h2af), histone2A1 (his2a1), histone cluster 1, H2A, III (HIST1H2A3), histone cluster 1, H2ac (HIST1H2AC), histone H2A (h2a-A), 5499, CG5499, DDBDRAFT_0205974, DDBDRAFT_0216271, DDB_0205974, DDB_0216271, Dmel\\CG5499, gamma-H2Av, gamma-HIS2AV, gamma-His2Av, gammaH2Av, H2A, H2a-221, H2A-III, H2A.F/Z, H2a.V, H2A.X, H2A.Z, H2AV, H2Av, H2av, H2AvD, H2avD, h2AvD, H2AV_DROM, H2AX, H2AZ, HIS, His, his, His2, HIS2AV, His2AV, HIS2AVD, His2AvD, HisH2Av, Hist, HIST1H2AA, Hist2av, l(3)05146, l(3)97Dd, l(3)810, l(3)L1602, RGD1564767Protein level used designations for Histone H2A
- CG5499-PA
- CG5499-PB
- H2A variant
- His2Av-PA
- His2Av-PB
- Histone-2A
- Histone2Av
- histone
- histone 2A variant
- histone H2A variant
- histone H2Av
- histone variant H2Av
- histone2A
- histone2AvD
- histone H2A
- Histone H2a
- histone 1, H2af
- histone H2A type 1-F
- histone H2a (aa 92-128)
- CL2029_4
- CL2029_4(696)
- CL2029_4_ov
- CL2029_4b
- H2A
- Zm.ov5
- p-Zm.ov5
- H2A histone
- histone H2A-III
- histone H2A type 1-C
您还需要查找其他产品吗？
- Histone H1.5
- Histone H1.3
- Histone H1.1
- Histone H1
- Histone H1
- Histone Cluster 3, H3
- Histone Cluster 2, H4a
- Histone Cluster 2, H3c
- Histone Cluster 2, H2bb
- Histone Cluster 1, H4b
- Histone Cluster 1, H3h
- Histone Cluster 1, H3g
- Histone Cluster 1, H1t
- Histone 3
- Histone 2b
- Histocompatibility 60a
- Histocompatibility 31 (H31)
- Histocompatibility 2, Q Region Locus 10
- Histocompatibility 2, Class II Antigen E Alpha, Pseudogene
- Histocompatibility (Minor) Serpin Domain Containing
- Histone H2A type 1-J
- Histone H2A Variant
- Histone H2A Variant H2A.Z, Pht1
- Histone H2A.2
- Histone H2B
- Histone H2B 5
- Histone H2B 7
- Histone H2B Type 1-C/E/F/G/I
- Histone H3.1
- Histone H3.1
- Histone H3.3
- Histone H3.3
- Histone H3.3B
- Histone H3.3C
- Histone H4
- Histone H4ac
- HIV
- HIV p17
- HIV Reverse Transcriptase
- HIV-1 Gag
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