Histone H2A 抗体
(Histone H2A)
Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Acts as a Polycomb group (PcG) protein required to maintain the transcriptionally repressive state of homeotic genes of the animal throughout development. Required for histone H3 'Lys-9' methylation and histone H4 'Lys-12' acetylation, two modifications that are essential for heterochromatin formation. Also involved in DNA double strand break (DSB) repair. Essential for early development.
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recommended
recommended
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Popular Histone H2A 抗体
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Cat. No.
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Human
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WB, IHC, IF
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- (7)
Cat. No.
ABIN7267725
Quantity
100 μL
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Datasheet
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Human
Application
WB, IHC, IF
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- (5)
Cat. No.
ABIN6136140
Quantity
100 μL
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Datasheet
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Human, Mouse, Rat
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IHC, IF
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- (4)
Cat. No.
ABIN7258522
Quantity
200 μL
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Human, Mouse, Rat
Application
WB, IHC, ELISA, IF, ICC
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- (3)
Cat. No.
ABIN6254871
Quantity
100 μL
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Datasheet
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Human
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WB, IF
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- (3)
Cat. No.
ABIN7267722
Quantity
100 μL
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Datasheet
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Human
Application
WB
Validations
- (1)
- (2)
Cat. No.
ABIN3023622
Quantity
100 μL
Datasheet
Datasheet
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Human, Rat
Application
IHC
Validations
- (2)
Cat. No.
ABIN7265302
Quantity
200 μL
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Datasheet
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Human
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WB, IF, DB
Validations
- (2)
Cat. No.
ABIN6971791
Quantity
100 μg
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Datasheet
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Human
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WB, DB
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- (2)
Cat. No.
ABIN6971785
Quantity
100 μL
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Datasheet
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Human
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WB, DB
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- (2)
Cat. No.
ABIN6971779
Quantity
100 μL
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Datasheet
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Human, Mouse, Rat
Application
WB, IHC, ELISA
Validations
- (2)
Cat. No.
ABIN6256470
Quantity
100 μL
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Datasheet
Reactivity
Human
Application
WB
Validations
- (2)
Cat. No.
ABIN6141572
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Saccharomyces cerevisiae
Application
WB, DB
Validations
- (1)
- (2)
Cat. No.
ABIN2668303
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Hamster, Human, Mouse, Rat
Application
WB, IF, IP
Validations
- (3)
Cat. No.
ABIN1107544
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC (p), IF (cc), FACS, IF (p), ICC, IHC (fro)
Validations
- (1)
Cat. No.
ABIN703991
Quantity
100 μL
Datasheet
Datasheet
Latest Publications for our Histone H2A 抗体
: "Molecular Signature and Mechanisms of Hepatitis D Virus-Associated Hepatocellular Carcinoma." in: Molecular cancer research : MCR, Vol. 16, Issue 9, pp. 1406-1419, (2018) (PubMed).: "Distinct histone methylation and transcription profiles are established during the development of cellular quiescence in yeast." in: BMC genomics, Vol. 18, Issue 1, pp. 107, (2017) (PubMed).
: "RNA m6A methylation regulates the ultraviolet-induced DNA damage response." in: Nature, Vol. 543, Issue 7646, pp. 573-576, (2017) (PubMed).
: "The transcription factor GATA3 is required for homologous recombination repair by regulating CtIP expression." in: Oncogene, Vol. 36, Issue 36, pp. 5168-5176, (2017) (PubMed).
: "PP2A Controls Genome Integrity by Integrating Nutrient-Sensing and Metabolic Pathways with the DNA Damage Response." in: Molecular cell, Vol. 67, Issue 2, pp. 266-281.e4, (2017) (PubMed).
: "Probing the catalytic functions of Bub1 kinase using the small molecule inhibitors BAY-320 and BAY-524." in: eLife, Vol. 5, (2017) (PubMed).
: "Borealin dimerization mediates optimal CPC checkpoint function by enhancing localization to centromeres and kinetochores." in: Nature communications, Vol. 6, pp. 6775, (2015) (PubMed).
: "Snf2h-mediated chromatin organization and histone H1 dynamics govern cerebellar morphogenesis and neural maturation. ..." in: Nature communications, Vol. 5, pp. 4181, (2014) (PubMed).
: "An RNA polymerase II-coupled function for histone H3K36 methylation in checkpoint activation and DSB repair." in: Nature communications, Vol. 5, pp. 3965, (2014) (PubMed).
: "The yeast Cyc8-Tup1 complex cooperates with Hda1p and Rpd3p histone deacetylases to robustly repress transcription of the subtelomeric FLO1 gene." in: Biochimica et biophysica acta, Vol. 1839, Issue 11, pp. 1242-55, (2014) (PubMed).
Aliases for Histone H2A 抗体
Histone H2A variant (His2Av) 抗体putative histone H2A (LMJF_17_0280) 抗体
histone H2A (H2AX) 抗体
histone cluster 1 H2A family member F (Hist1h2af) 抗体
histone H2A-like (LOC100425378) 抗体
histone cluster 1, H2af (Hist1h2af) 抗体
histone2A1 (his2a1) 抗体
histone cluster 1, H2A, III (HIST1H2A3) 抗体
histone cluster 1, H2ac (HIST1H2AC) 抗体
histone H2A (h2a-A) 抗体
5499 抗体
CG5499 抗体
DDBDRAFT_0205974 抗体
DDBDRAFT_0216271 抗体
DDB_0205974 抗体
DDB_0216271 抗体
Dmel\\CG5499 抗体
gamma-H2Av 抗体
gamma-HIS2AV 抗体
gamma-His2Av 抗体
gammaH2Av 抗体
H2A 抗体
H2a-221 抗体
H2A-III 抗体
H2A.F/Z 抗体
H2a.V 抗体
H2A.X 抗体
H2A.Z 抗体
H2AV 抗体
H2Av 抗体
H2av 抗体
H2AvD 抗体
H2avD 抗体
h2AvD 抗体
H2AV_DROM 抗体
H2AX 抗体
H2AZ 抗体
HIS 抗体
His 抗体
his 抗体
His2 抗体
HIS2AV 抗体
His2AV 抗体
HIS2AVD 抗体
His2AvD 抗体
HisH2Av 抗体
Hist 抗体
HIST1H2AA 抗体
Hist2av 抗体
l(3)05146 抗体
l(3)97Dd 抗体
l(3)810 抗体
l(3)L1602 抗体
RGD1564767 抗体
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