电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

RANGAP1 抗体

RANGAP1 适用: 人, 小鼠, 大鼠 WB, IHC (p), FACS, IF (cc), IF (p) 宿主: 兔 Monoclonal 2A1 unconjugated
产品编号 ABIN6944745
发货至: 中国
  • 抗原 See all RANGAP1 抗体
    RANGAP1 (Ran GTPase Activating Protein 1 (RANGAP1))
    适用
    • 53
    • 25
    • 24
    • 5
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 45
    • 5
    • 2
    • 1
    克隆类型
    • 42
    • 11
    单克隆
    标记
    • 29
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This RANGAP1 antibody is un-conjugated
    应用范围
    • 35
    • 25
    • 19
    • 11
    • 5
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    Recombinant protein within human RanGAP1 aa 1-200.
    克隆位点
    2A1
    亚型
    IgG
    Top Product
    Discover our top product RANGAP1 Primary Antibody
  • 应用备注
    WB 1:300-5000
    FCM 1:20-100
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    RANGAP1 (Ran GTPase Activating Protein 1 (RANGAP1))
    别名
    RanGAP1 (RANGAP1 产品)
    别名
    Fug1 antibody, RANGAP antibody, SD antibody, ATRANGAP1 antibody, RAN GTPASE-ACTIVATING PROTEIN 1 antibody, RAN GTPase activating protein 1 antibody, RanGAP1 antibody, fug1 antibody, rangap1b antibody, rna1p antibody, C79654 antibody, mKIAA1835 antibody, rangap1 antibody, rangap1a antibody, Protein rna1 antibody, CG9999 antibody, CT28175 antibody, Dmel\CG9999 antibody, RGP1_DROME antibody, Ran antibody, RanGAP antibody, RanGap antibody, RanGap1 antibody, Scl antibody, Sd antibody, Sd-RanGAP antibody, Sd-RanGap antibody, dRanGAP antibody, ranGAP antibody, ranGap antibody, rangap antibody, zgc:154097 antibody, Ran GTPase activating protein 1 antibody, RAN GTPase activating protein 1 antibody, ran GTPase activating protein 1 antibody, Ran GTPase activating protein 1 S homeolog antibody, Ran GTPase activating protein 1 L homeolog antibody, Ran GAP Rna1 antibody, Ran GTPase activating protein antibody, RAN GTPase activating protein 1a antibody, RANGAP1 antibody, TERG_02084 antibody, rangap1.S antibody, Rangap1 antibody, rangap1.L antibody, rna1 antibody, RanGAP antibody, rangap1a antibody
    背景

    Synonyms: Ran GTPase-activating protein 1, RanGAP1, RANGAP1, KIAA1835

    Background: The small Ras related protein Ran, also called TC4, is a nuclear localized GTPase implicated in a diverse array of cellular processes including DNA replication, entry into and exit from mitosis and the transport of RNA and proteins through the nuclear pore complex. Like Ras, active Ran GTP and inactive Ran GDP levels are tightly regulated by guanine nucleotide exchange factors (GEFs) and GTPase-activating proteins (GAPs). The abundant GEF RCC1 (regulator of chromosome condensation 1) increases the rate at which Ran exchanges GDP for GTP. Ran GAP1 opposes the effects of RCC1 by increasing the rate at which Ran hydrolyzes GTP to GDP. A protein designated Ran BP1 has no intrinsic GAP activity and functions as a GEF inhibitor deactivating RCC1 and thereby indirectly increasing the ratio of Ran GDP to Ran GTP. Ran BP2 has been proposed as the Ran GTP docking site at the periphery of the nuclear pore complex.

    基因ID
    5905
    UniProt
    P46060
    途径
    M Phase, Protein targeting to Nucleus
You are here:
客服