ARPC5 抗体
-
- 抗原 See all ARPC5 抗体
- ARPC5 (Actin Related Protein 2/3 Complex, Subunit 5, 16kDa (ARPC5))
-
适用
- 人, 大鼠, 小鼠
-
宿主
- 兔
-
克隆类型
- 单克隆
-
标记
- This ARPC5 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- Recombinant human p16 ARC around N-terminus
- 克隆位点
- 8D8
- 亚型
- IgG
- Top Product
- Discover our top product ARPC5 Primary Antibody
-
-
- 应用备注
-
WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF(ICC) 1:50-200
IHC() - 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
-
- 抗原
- ARPC5 (Actin Related Protein 2/3 Complex, Subunit 5, 16kDa (ARPC5))
- 别名
- p16 ARC (ARPC5 产品)
- 别名
- arc16 antibody, p16-arc antibody, ARPC5 antibody, APOBEC4 antibody, ARC16 antibody, dJ127C7.3 antibody, p16-Arc antibody, MGC86407 antibody, 5830443F10Rik antibody, arpc5 antibody, fb09c07 antibody, fb12b05 antibody, fc56c07 antibody, wu:fb09c07 antibody, wu:fb12b05 antibody, wu:fc56c07 antibody, actin related protein 2/3 complex subunit 5 antibody, actin related protein 2/3 complex subunit 5 L homeolog antibody, actin related protein 2/3 complex, subunit 5 antibody, actin related protein 2/3 complex, subunit 5B antibody, actin related protein 2/3 complex, subunit 5A antibody, ARPC5 antibody, arpc5 antibody, arpc5.L antibody, Arpc5 antibody, arpc5b antibody, arpc5a antibody
- 背景
-
Synonyms: Actin-related protein 2/3 complex subunit 5, Arp2/3 complex 16 kDa subunit, p16-ARC, ARPC5
Background: Component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (PubMed:9230079). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility (PubMed:9230079). In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA (PubMed:29925947). The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs).
- 基因ID
- 10092
- UniProt
- O15511
- 途径
- RTK signaling, Regulation of Actin Filament Polymerization
-