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METAP2 抗体

METAP2 适用: 人, 小鼠, 大鼠 WB, IHC (p), FACS, IF (cc), IF (p) 宿主: 兔 Monoclonal 2G3 unconjugated
产品编号 ABIN6944076
发货至: 中国
  • 抗原 See all METAP2 抗体
    METAP2 (Methionyl Aminopeptidase 2 (METAP2))
    适用
    • 67
    • 13
    • 11
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 62
    • 4
    • 1
    克隆类型
    • 56
    • 11
    单克隆
    标记
    • 30
    • 6
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This METAP2 antibody is un-conjugated
    应用范围
    • 47
    • 35
    • 16
    • 7
    • 5
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    Recombinant protein within C-terminal human Methionine Aminopeptidase 2.
    克隆位点
    2G3
    亚型
    IgG
    Top Product
    Discover our top product METAP2 Primary Antibody
  • 应用备注
    WB 1:300-5000
    FCM 1:20-100
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for 12 months.
    有效期
    12 months
  • 抗原
    METAP2 (Methionyl Aminopeptidase 2 (METAP2))
    别名
    METAP2 (METAP2 产品)
    别名
    metap2 antibody, MGC53792 antibody, METAP2 antibody, GB13458 antibody, DDBDRAFT_0190923 antibody, DDBDRAFT_0304991 antibody, DDB_0190923 antibody, DDB_0304991 antibody, 4930584B20Rik antibody, A930035J23Rik antibody, AI047573 antibody, AL024412 antibody, AU014659 antibody, Amp2 antibody, Mnpep antibody, p67 antibody, p67eIF2 antibody, MAP2 antibody, MNPEP antibody, wu:fb98h06 antibody, zgc:66250 antibody, methionyl aminopeptidase 2 L homeolog antibody, methionyl aminopeptidase 2 antibody, methionine aminopeptidase 2 antibody, methionine aminopeptidase antibody, methionyl aminopeptidase 2 S homeolog antibody, methionyl aminopeptidase 2b antibody, metap2.L antibody, METAP2 antibody, metap2 antibody, LOC551771 antibody, CAALFM_C604080WA antibody, Metap2 antibody, metap2.S antibody, metap2b antibody
    背景

    Synonyms: Methionine aminopeptidase 2, Initiation factor 2-associated 67 kDa glycoprotein, Peptidase M, MetAP 2, p67, p67eIF2, METAP2, MNPEP, P67EIF2

    Background: Methionine aminopeptidases (MetAP), also designated peptidase M proteins, are members of the M24 family of proteins. Both MetAP-1 and MetAP-2 release N-terminal amino acids, usually methionine, from nascent peptides and arylamines. Eukaryotes contain both MetAP-1 and MetAP-2, whereas prokaryotes possess only the MetAP-1 enzyme. MetAP-1 and MetAP-2 control cell proliferation in mammalian cells. MetAP-2 is highly conserved between human and Saccharomyces cerevisiae. Neurofibromin (NF1) regulates MetAp-2 and increased expression of MetAP-2 correlates with several forms of cancer. Inhibitors of MetAP-2 are potential targets in cancer therapeutics, particularly in NF1-associated tumor proliferation. Chemotherapeutic drugs such as ovalicin and fumagillin bind to the active site of and inhibit MetAp-2.

    基因ID
    10988
    UniProt
    P50579
    途径
    Regulation of G-Protein Coupled Receptor Protein Signaling
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