SETD8 抗体
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- 抗原 See all SETD8 抗体
- SETD8 (SET Domain Containing (Lysine Methyltransferase) 8 (SETD8))
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 单克隆
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标记
- This SETD8 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS)
- 交叉反应
- 人, 小鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- Synthetic peptide within human KMT5A 50-100
- 克隆位点
- 2A1
- 亚型
- IgG
- Top Product
- Discover our top product SETD8 Primary Antibody
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anti-SET Domain Containing (Lysine Methyltransferase) 8 (SETD8) (AA 109-272) antibody
SETD8 适用: 人 WB, ELISA, IHC, ICC, FACS, Neut 宿主: 小鼠 Monoclonal 7H1G10 unconjugated
anti-SET Domain Containing (Lysine Methyltransferase) 8 (SETD8) (N-Term) antibodySETD8 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 小鼠 Monoclonal 43AT551-86 unconjugated
anti-SET Domain Containing (Lysine Methyltransferase) 8 (SETD8) (AA 25-53) antibodySETD8 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-SET Domain Containing (Lysine Methyltransferase) 8 (SETD8) (N-Term) antibodySETD8 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Monoclonal 43AT551-86 unconjugated
anti-SET Domain Containing (Lysine Methyltransferase) 8 (SETD8) (AA 73-352) antibodySETD8 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-SET Domain Containing (Lysine Methyltransferase) 8 (SETD8) (AA 220-249) antibodySETD8 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB18964 unconjugated
anti-SET Domain Containing (Lysine Methyltransferase) 8 (SETD8) (AA 136-258) antibodySETD8 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-SET Domain Containing (Lysine Methyltransferase) 8 (SETD8) antibodySETD8 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-SET Domain Containing (Lysine Methyltransferase) 8 (SETD8) antibodySETD8 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-SET Domain Containing (Lysine Methyltransferase) 8 (SETD8) (N-Term) antibodySETD8 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:300-5000
FCM 1:20-100 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- SETD8 (SET Domain Containing (Lysine Methyltransferase) 8 (SETD8))
- 别名
- KMT5A (SETD8 产品)
- 别名
- KMT5A antibody, PR-Set7 antibody, SET07 antibody, SET8 antibody, 2410195B05Rik antibody, AA617402 antibody, AW536475 antibody, PR-SET7 antibody, setd8b antibody, wu:fc23f12 antibody, zgc:171649 antibody, Pr-set7 antibody, RGD1305893 antibody, Setd8 antibody, kmt5a antibody, kmt5a-a antibody, setd8 antibody, setd8-a antibody, set8a antibody, setd8a antibody, wu:fj33f02 antibody, zgc:153719 antibody, lysine methyltransferase 5A antibody, lysine methyltransferase 5Ab antibody, lysine methyltransferase 5A S homeolog antibody, lysine methyltransferase 5Aa antibody, KMT5A antibody, Kmt5a antibody, kmt5ab antibody, kmt5a.S antibody, kmt5aa antibody
- 背景
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Synonyms: N-lysine methyltransferase KMT5A, H4-K20-HMTase KMT5A, Histone-lysine N-methyltransferase KMT5A, Lysine N-methyltransferase 5A, Lysine-specific methylase 5A, PR/SET domain-containing protein 07, SET domain-containing protein 8, PR-Set7, PR/SET07, KMT5A, PRSET7, SET07, SET8, SETD8
Background: Protein-lysine N-methyltransferase that monomethylates both histones and non-histone proteins. Specifically monomethylates 'Lys-20' of histone H4 (H4K20me1). H4K20me1 is enriched during mitosis and represents a specific tag for epigenetic transcriptional repression. Mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes. Required for cell proliferation, probably by contributing to the maintenance of proper higher-order structure of DNA during mitosis. Involved in chromosome condensation and proper cytokinesis. Nucleosomes are preferred as substrate compared to free histones. Mediates monomethylation of p53/TP53 at 'Lys-382', leading to repress p53/TP53-target genes. Plays a negative role in TGF-beta response regulation and a positive role in cell migration.
- 基因ID
- 387893
- UniProt
- Q9NQR1
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