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KDM5A 抗体

KDM5A 适用: 人 WB, IF (cc), FACS 宿主: 兔 Monoclonal 1G8 unconjugated
产品编号 ABIN6943881
发货至: 中国
  • 抗原 See all KDM5A 抗体
    KDM5A (Lysine (K)-Specific Demethylase 5A (KDM5A))
    适用
    • 67
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    宿主
    • 61
    • 5
    克隆类型
    • 55
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    单克隆
    标记
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    This KDM5A antibody is un-conjugated
    应用范围
    • 46
    • 25
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    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Flow Cytometry (FACS)
    交叉反应
    纯化方法
    Purified by Protein A.
    免疫原
    Recombinant protein within human KDM5A aa 1500-1690
    克隆位点
    1G8
    亚型
    IgG
    Top Product
    Discover our top product KDM5A Primary Antibody
  • 应用备注
    WB 1:300-5000
    FCM 1:20-100
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    KDM5A (Lysine (K)-Specific Demethylase 5A (KDM5A))
    别名
    KDM5A (KDM5A 产品)
    别名
    Jarid1a antibody, JARID1A antibody, RBBP-2 antibody, RBBP2 antibody, RBP2 antibody, AA409370 antibody, C76986 antibody, Rbbp2 antibody, lysine demethylase 5A antibody, lysine (K)-specific demethylase 5A antibody, Kdm5a antibody, KDM5A antibody
    背景

    Synonyms: Lysine-specific demethylase 5A, Histone demethylase JARID1A, Jumonji/ARID domain-containing protein 1A, Retinoblastoma-binding protein 2, RBBP-2, KDM5A, JARID1A, RBBP2, RBP2

    Background: Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. May stimulate transcription mediated by nuclear receptors. May be involved in transcriptional regulation of Hox proteins during cell differentiation. May participate in transcriptional repression of cytokines such as CXCL12. Plays a role in the regulation of the circadian rhythm and in maintaining the normal periodicity of the circadian clock. In a histone demethylase-independent manner, acts as a coactivator of the CLOCK-ARNTL/BMAL1-mediated transcriptional activation of PER1/2 and other clock-controlled genes and increases histone acetylation at PER1/2 promoters by inhibiting the activity of HDAC1.

    基因ID
    5927
    UniProt
    P29375
    途径
    Chromatin Binding, Warburg Effect
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